A Comparative Analysis of TSH Levels between Patients with Normal Sinus Rhythm and those with Atrial Fibrillation

Ji Yeon Chang; Jae Kyung Kim; Seung Hee Hong

doi:10.3844/ajbbsp.2024.243.249

Article Details

A Comparative Analysis of TSH Levels between Patients with Normal Sinus Rhythm and those with Atrial Fibrillation

Authors:

Ji Yeon Chang | Jae Kyung Kim | Seung Hee Hong

Publisher:

Science Publications

Journal:

American Journal of Biochemistry and Biotechnology Vol.20 Issue 3, pp.243-249

Document Type:

Article

Publication Date:

7/2024

Document Language:

English

Document ID (Org No.):

2001397569

pISSN:

1558-6332

DOI:

10.3844/ajbbsp.2024.243.249

Keywords:

Abstract:

 Atrial Fibrillation (AF) is the most prevalent persistent cardiac arrhythmia observed within the general population and is associated with increased morbidity and mortality. Despite the rising global prevalence of AF, the majority of existing studies have primarily focused on white populations. For that reason, we have used a Korean hospital patient's blood test results to examine the link between AF and certain blood test results. Conducted at a tertiary medical institution, this retrospective study included patients with Normal Sinus Rhythm (NSR) and AF, excluding those on thyroid medications at diagnosis. Initially, 200 patients were evaluated, with 36 excluded, leaving 164 for the final analysis. In the NSR group, the average Thyroid Stimulating Hormone (TSH) level was 1.88 (normal range: 0.41-4.3 uIU/mL), with a standard deviation of 1.27. In the AF group, the average TSH level was 2.48, with a standard deviation of 1.91 (p = 0.018). AF was associated with both hyperthyroidism and hypothyroidism, which appeared to be a common precursor of thyroid dysfunction. The study highlights clinical risk factors for thyroid dysfunction in AF patients, despite limitations such as a small sample size and potential detection bias due to unrecognized new-onset AF.

Article Details

A Comparative Analysis of TSH Levels between Patients with Normal Sinus Rhythm and those with Atrial Fibrillation

Authors:

Ji Yeon Chang | Jae Kyung Kim | Seung Hee Hong

Publisher:

Science Publications

Journal:

American Journal of Biochemistry and Biotechnology Vol.20 Issue 3, pp.243-249

Document Type:

Article

Publication Date:

7/2024

Document Language:

English

Document ID (Org No.):

2001397569

pISSN:

1558-6332

DOI:

10.3844/ajbbsp.2024.243.249

Arrhythmia

Atrial Fibrillation

Hyperthyroidism

Thyroid-Stimulating Hormone

Issues

Article Details

A Comparative Analysis of TSH Levels between Patients with Normal Sinus Rhythm and those with Atrial Fibrillation

Authors: Ji Yeon Chang | Jae Kyung Kim | Seung Hee Hong

Publisher: Science Publications

Journal: American Journal of Biochemistry and Biotechnology Vol.20 Issue 3, pp.243-249

Document Type: Article

Publication Date: 7/2024

Document Language: English

Document ID (Org No.): 2001397569

pISSN: 1558-6332

DOI: 10.3844/ajbbsp.2024.243.249

Arrhythmia

Atrial Fibrillation

Hyperthyroidism

Thyroid-Stimulating Hormone

Issues

Authors:

Ji Yeon Chang | Jae Kyung Kim | Seung Hee Hong

Publisher:

Science Publications

Journal:

American Journal of Biochemistry and Biotechnology Vol.20 Issue 3, pp.243-249

Document Type:

Article

Publication Date:

7/2024

Document Language:

English

Document ID (Org No.):

2001397569

pISSN:

1558-6332

DOI:

10.3844/ajbbsp.2024.243.249