Efficacy of Viola Odorata Flower Decoction in Chronic Rhinosinusitis

Mulla , Imamuddin; Roqaiya , Mariyam; Khan , Mohd Imran

doi:10.5505/ias.2019.08379

Article Details

Efficacy of Viola Odorata Flower Decoction in Chronic Rhinosinusitis

Authors:

Mulla , Imamuddin | Roqaiya , Mariyam | Khan , Mohd Imran

Publisher:

Islamic World Academy of Sciences

Main Topics:

Medicine

Journal:

Medical Journal of Islamic World Academy of Sciences 2019 Vol.27 Issue 3, pp.77-84

Document Type:

Article

Publication Date:

7/2019

Document Language:

English

Document ID (Org No.):

244215

Frequency:

Quarterly

pISSN:

10163360

DOI:

10.5505/ias.2019.08379

Descriptors:

Keywords:

Abstract:

 Chronic rhinosinusitis (CRS) is one of the most frequent otorhinolaryngologic diseases encountered in daily practice withan estimated prevalence of 14% of the global population. This study aimed to explore the efficacy of Viola odorata flowerdecoction against CRS.In this prospective randomized controlled trial, 30 patients with CRS were randomly assigned to receive either test drug (10g of V. odorata flower in the form of decoction administered orally empty stomach in the morning daily) or active control drug(single nasal spray of fluticasone propionate 50 μg/spray in each nostril daily) for 30 days. The primary outcome measure wasan improvement in sinonasal symptoms assessed using a 22-item sinonasal outcome questionnaire (SNOT-22). Reduction inabsolute eosinophil count (AEC) and improvement in x-ray paranasal sinus were secondary outcome measures. The significancelevel was kept as 5%.After completing the therapy, the SNOT-22 score was significantly low in the test group compared with the control groupand a significant difference was found in AEC between the groups. Also, the SNOT-22 score remained significantly low aftercompletion of the treatment on the 45th and 60th days compared with the control drug. Changes in x-ray paranasal sinuses werenot significant between the groups. These results suggested that V. odorata flower was effective in reducing the symptoms of CRS.Trial Registration No. Clinical Trial Registry of India CTRI/2017/09/009788 (01/09/2016)

Article Details

Efficacy of Viola Odorata Flower Decoction in Chronic Rhinosinusitis

Authors:

Mulla , Imamuddin | Roqaiya , Mariyam | Khan , Mohd Imran

Publisher:

Islamic World Academy of Sciences

Main Topics:

Medicine

Journal:

Medical Journal of Islamic World Academy of Sciences 2019 Vol.27 Issue 3, pp.77-84

Document Type:

Article

Publication Date:

7/2019

Document Language:

English

Document ID (Org No.):

244215

Frequency:

Quarterly

pISSN:

10163360

DOI:

10.5505/ias.2019.08379

Descriptors:

HERBAL MEDICINE

TRADITIONAL MEDICINE

QUALITY OF LIFE

FLOWERS

VIOLA

Flower

Herbal Medicine

Quality of Life

Sinonasal

Viola Odorata

Issues

Article Details

Authors: Mulla , Imamuddin | Roqaiya , Mariyam | Khan , Mohd Imran

Publisher: Islamic World Academy of Sciences

Main Topics: Medicine

Journal: Medical Journal of Islamic World Academy of Sciences 2019 Vol.27 Issue 3, pp.77-84

Document Type: Article

Publication Date: 7/2019

Document Language: English

Document ID (Org No.): 244215

Frequency: Quarterly

pISSN: 10163360

DOI: 10.5505/ias.2019.08379

Descriptors:

Issues

Authors:

Mulla , Imamuddin | Roqaiya , Mariyam | Khan , Mohd Imran

Publisher:

Islamic World Academy of Sciences

Main Topics:

Medicine

Journal:

Medical Journal of Islamic World Academy of Sciences 2019 Vol.27 Issue 3, pp.77-84

Document Type:

Article

Publication Date:

7/2019

Document Language:

English

Document ID (Org No.):

244215

Frequency:

Quarterly

pISSN:

10163360

DOI:

10.5505/ias.2019.08379