Antioxidant Effect of Flaxseed Against Liver Cirrhosis Induced in Thioacetamide  Intoxicated Rats

Wafaa Gh. Shousha; Hatem A. El-Mezayen; Shawkia S. Abdul-Halim; Elham A. Mohmmed

doi:10.12816/0000860

Article Details

Antioxidant Effect of Flaxseed Against Liver Cirrhosis Induced in Thioacetamide Intoxicated Rats

Authors:

Wafaa Gh. Shousha | Hatem A. El-Mezayen | Shawkia S. Abdul-Halim | Elham A. Mohmmed

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2013 vol.51, pp.448-460

Document Type:

Article

Publication Date:

4/2013

Document Language:

English

Document ID (Org No.):

35640

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

DOI:

10.12816/0000860

Descriptors:

Keywords:

Abstract:

 Background/Aim:There has been a current upsurge in the medical implications of free radicals and related species during the past several decades. These chemical species are integral components produced during normal biochemical and physiological processes but leads to oxidative stress when produce in excess and causes potential damage to cells. A wide range of non-enzymatic and enzymatic antioxidant defenses exists to counteract the damaging effects of free radicals. There exist epidemiological evidences correlating higher intake of antioxidant rich foodstuffs with greater free radical neutralizing potential to lower incidence of several human morbidities or mortalities.

Material andMethods: liver cirrhosis model was induced by TAA,hepatobichemical and antioxidant parameters were assayed.
Results: Flaxseed induced enhancement in liver function test, antioxidant status and lipid profile.
Conclusion: Flaxseed can be used as hepatoprotective against liver cirrhosis induced with TAA as compared to reference drug Silymaringroup.
Keyword: liver Cirrhosis, Thioacetamide , Flax seed , Silymarin, Antioxidant.

Article Details

Antioxidant Effect of Flaxseed Against Liver Cirrhosis Induced in Thioacetamide Intoxicated Rats

Authors:

Wafaa Gh. Shousha | Hatem A. El-Mezayen | Shawkia S. Abdul-Halim | Elham A. Mohmmed

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2013 vol.51, pp.448-460

Document Type:

Article

Publication Date:

4/2013

Document Language:

English

Document ID (Org No.):

35640

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

DOI:

10.12816/0000860

Descriptors:

LINSEED

BILIARY CIRRHOSIS

HEPATITIS

APPENDIX

ANTIOXIDANTS

METABOLISM

LABORATORY ANIMALS

liver Cirrhosis

Thioacetamide

Flax seed

Silymarin

Antioxidant

Issues

Article Details

Authors: Wafaa Gh. Shousha | Hatem A. El-Mezayen | Shawkia S. Abdul-Halim | Elham A. Mohmmed

Publisher: Pan Arab League of Continuous Medical Education

Main Topics: Medicine

Journal: The Egyptian Journal of Hospital Medicine 2013 vol.51, pp.448-460

Document Type: Article

Publication Date: 4/2013

Document Language: English

Document ID (Org No.): 35640

Frequency: Quarterly

eISSN: 20907125

pISSN: 16872002

DOI: 10.12816/0000860

Descriptors:

Issues

Authors:

Wafaa Gh. Shousha | Hatem A. El-Mezayen | Shawkia S. Abdul-Halim | Elham A. Mohmmed

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2013 vol.51, pp.448-460

Document Type:

Article

Publication Date:

4/2013

Document Language:

English

Document ID (Org No.):

35640

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

DOI:

10.12816/0000860