The diagnostic accuracy of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in mediastinal tuberculous lymphadenitis

Onur Fevzi ERER; Serhat EROL; Ceyda ANAR; Can BİÇMEN; Zekiye AYDOĞDU; Serir ÖZKAN

Article Details

The diagnostic accuracy of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in mediastinal tuberculous lymphadenitis

Authors:

Onur Fevzi ERER | Serhat EROL | Ceyda ANAR | Can BİÇMEN | Zekiye AYDOĞDU | Serir ÖZKAN

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 6, pp.1874-1879

Document Type:

Article

Publication Date:

11/2017

Document Language:

Turkish

Document ID (Org No.):

2000751033

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Abstract:

 

Background/aim: Mediastinal lymph nodes are the second most commonly affected lymph nodes in tuberculous lymphadenitis. It is often difficult to diagnose tuberculosis in patients with lymphadenopathy without parenchymal lesions. The aim of this study was to describe the diagnostic utility of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with isolated mediastinal tuberculous lymphadenitis (MTLA). Materials and methods: This study included 527 patients who had undergone EBUS-TBNA between December 2012 and December 2014. Patients with the final diagnosis of MTLA were evaluated. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of EBUS-TBNA were calculated.Results: The prevalence of MTLA in all patients who had undergone EBUS-TBNA for mediastinal lymphadenopathy of unknown etiology was 5.2% (28/527). EBUS-TBNA was diagnostic in 21/28 (75%) patients, and the remaining 7 patients required additional procedures for confirmation of diagnosis. Sensitivity, specificity, PPV, NPV, and accuracy of combined cytopathological and microbiological examinations of EBUS-TBNA in the diagnosis of MTLA were 87.5%, 98.5%, 91.4%, 98%, and 94.4%, respectively. There were no major complications.Conclusion: EBUS-TBNA is a safe and effective procedure for the diagnosis of MTLA. When microbiological and cytopathological examinations of samples are combined, EBUS-TBNA demonstrates good diagnostic accuracy and NPV for the diagnosis of MTLA.

Article Details

The diagnostic accuracy of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in mediastinal tuberculous lymphadenitis

Authors: Onur Fevzi ERER | Serhat EROL | Ceyda ANAR | Can BİÇMEN | Zekiye AYDOĞDU | Serir ÖZKAN

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2017 Vol.47 Issue 6, pp.1874-1879

Document Type: Article

Publication Date: 11/2017

Document Language: Turkish

Document ID (Org No.): 2000751033

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Issues

Authors:

Onur Fevzi ERER | Serhat EROL | Ceyda ANAR | Can BİÇMEN | Zekiye AYDOĞDU | Serir ÖZKAN

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2017 Vol.47 Issue 6, pp.1874-1879

Document Type:

Article

Publication Date:

11/2017

Document Language:

Turkish

Document ID (Org No.):

2000751033

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144