Serum and Follicular Fluid Vitamin D and Follicular Response among Infertile Women Undergoing ICSI

Sedighe Esmaeilzadeh; Maryam Aliasgharpour; Parvaneh Mirabi; Azita Ghanbarpour; Maede Fasihian

doi:10.5742/MEWFM.2017.93011

Article Details

Serum and Follicular Fluid Vitamin D and Follicular Response among Infertile Women Undergoing ICSI

Authors:

Sedighe Esmaeilzadeh | Maryam Aliasgharpour | Parvaneh Mirabi | Azita Ghanbarpour | Maede Fasihian

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2017 Vol.15 Issue 7, pp.13-20

Document Type:

Article

Publication Date:

9/2017

Document Language:

English

Document ID (Org No.):

109655

Frequency:

Monthly

eISSN:

18390196

pISSN:

18390188

DOI:

10.5742/MEWFM.2017.93011

Descriptors:

Keywords:

Abstract:

 Background: Some studies have shown the relation between vitamin D levels and the success rate of fertility in couples treated with Assisted Reproductive Technology (ART). The aim of this study is to determine Association of vitamin D level in serum and follicular fluid with follicular response in infertile women in an ART program.
Method: In this cross sectional study 81 infertile women were placed under treatment for induction ovulation according to a long protocol. Follicular fluids were extracted from follicles over 14 mm and blood samples collected on the same day. Follicular fluid and blood samples were centrifuged and stored at -80 C. Then level of 25-OH-vit D was measured by immunoassay method.
Result: The mean age of the subjects was 32.91 ± 4.83. The average BMI of patients was 27.63 ± 3.97. There was no significant correlation between the follicular concentrations of vitamin D and the number of oocytes as well as serum concentration of vitamin D and the number of oocytes (Respectively, P = 0.95 and P = 057). There was also no relation between the numbers of ovarian follicles and follicular concentrations of vitamin D as well as the number of ovarian follicles and serum concentration of vitamin D (P=0.07).
Correlation analysis revealed a high relationship between serum and follicular fluid vitamin D (P<0.001).
Conclusion: Different concentrations of vitamin D in serum or follicles have no significant correlation with the number of ovarian follicles and mature oocytes.

Article Details

Serum and Follicular Fluid Vitamin D and Follicular Response among Infertile Women Undergoing ICSI

Authors:

Sedighe Esmaeilzadeh | Maryam Aliasgharpour | Parvaneh Mirabi | Azita Ghanbarpour | Maede Fasihian

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2017 Vol.15 Issue 7, pp.13-20

Document Type:

Article

Publication Date:

9/2017

Document Language:

English

Document ID (Org No.):

109655

Frequency:

Monthly

eISSN:

18390196

pISSN:

18390188

DOI:

10.5742/MEWFM.2017.93011

Descriptors:

FEMALE INFERTILITY

INFERTILITY

OVARIAN DISEASES

GYNECOLOGIC DISEASES

WOMEN

PATIENTS

Vitamin D

Infertility

Intracytoplasmic Sperm Injection

Oocyte

Follicular Fluid

Issues

Article Details

Authors: Sedighe Esmaeilzadeh | Maryam Aliasgharpour | Parvaneh Mirabi | Azita Ghanbarpour | Maede Fasihian

Publisher: medi+WORLD International

Main Topics: Medicine

Journal: World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2017 Vol.15 Issue 7, pp.13-20

Document Type: Article

Publication Date: 9/2017

Document Language: English

Document ID (Org No.): 109655

Frequency: Monthly

eISSN: 18390196

pISSN: 18390188

DOI: 10.5742/MEWFM.2017.93011

Descriptors:

Issues

Authors:

Sedighe Esmaeilzadeh | Maryam Aliasgharpour | Parvaneh Mirabi | Azita Ghanbarpour | Maede Fasihian

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2017 Vol.15 Issue 7, pp.13-20

Document Type:

Article

Publication Date:

9/2017

Document Language:

English

Document ID (Org No.):

109655

Frequency:

Monthly

eISSN:

18390196

pISSN:

18390188

DOI:

10.5742/MEWFM.2017.93011