The Effect of Vitamin D Level on the Clinical Situation in COVID-19 Patients

Fatih Davran; Ceyhan Hacıoğlu; Eda Kayabaşı; Banu Hümeyra Keskin; Pelin Duran; Elif Nisa Unlu; Elif Eşcan; Şengül Cangür; Cihadiye Elif Öztürk

Article Details

The Effect of Vitamin D Level on the Clinical Situation in COVID-19 Patients

Authors:

Fatih Davran | Ceyhan Hacıoğlu | Eda Kayabaşı | Banu Hümeyra Keskin | Pelin Duran | Elif Nisa Unlu | Elif Eşcan | Şengül Cangür | Cihadiye Elif Öztürk

Publisher:

Duzce University

Main Topics:

Health Care Administration

Journal:

Konuralp Medical Journal Vol.15 Issue 1, pp.130-135

Document Type:

Article

Publication Date:

3/2023

Document Language:

English

Document ID (Org No.):

2001285278

pISSN:

1309-3878

Keywords:

Abstract:

 Objective: Vitamin D plays an important role in maintaining the integrity of mucosal barriers and in natural and acquired immunity. In the COVID-19 pandemic, the strength of personal immunity is very important in the severe or lightening of the disease, even if there are variants of the virus or if you are vaccinated. Methods: In this study, we investigated the relationship between the clinical course and vitamin D levels of outpatient and inpatient follow-up patients admitted to our hospital due to COVID-19. A total of 94 patients, 47 outpatients and 47 inpatients, were included in the study. Result: The mean age and gender distributions of both groups were similar. Vitamin D levels were found to be normal in only 7 of 94 patients who were followed up in our hospital due to COVID-19. Patients with vitamin D levels 30 were significantly lower than those with 10 and 10-29.9 p0.01 for each. Hospitalized patients 71 with vitamin D levels 10 were significantly higher than those 0 with vitamin D levels 30. Additionally, the outpatients 29 with vitamin D levels 10 were significantly lower than those 100 with vitamin D levels 30. Conclusion: We showed that vitamin D deficiency may be associated with the severe clinical course of COVID-19, even in patients without comorbidities, and may also be one of the predisposing factors resulting in death in COVID-19. The data suggest that it is crucial to continue vitamin D supplements during the COVID-19 pandemic.

 Objective: Vitamin D plays an important role in maintaining the integrity of mucosal barriers and in natural and acquired immunity. In the COVID-19 pandemic, the strength of personal immunity is very important in the severe or lightening of the disease, even if there are variants of the virus or if you are vaccinated. Methods: In this study, we investigated the relationship between the clinical course and vitamin D levels of outpatient and inpatient follow-up patients admitted to our hospital due to COVID-19. A total of 94 patients, 47 outpatients and 47 inpatients, were included in the study. Result: The mean age and gender distributions of both groups were similar. Vitamin D levels were found to be normal in only 7 of 94 patients who were followed up in our hospital due to COVID-19. Patients with vitamin D levels 30 were significantly lower than those with 10 and 10-29.9 p0.01 for each. Hospitalized patients 71 with vitamin D levels 10 were significantly higher than those 0 with vitamin D levels 30. Additionally, the outpatients 29 with vitamin D levels 10 were significantly lower than those 100 with vitamin D levels 30. Conclusion: We showed that vitamin D deficiency may be associated with the severe clinical course of COVID-19, even in patients without comorbidities, and may also be one of the predisposing factors resulting in death in COVID-19. The data suggest that it is crucial to continue vitamin D supplements during the COVID-19 pandemic.

 Objective: Vitamin D plays an important role in maintaining the integrity of mucosal barriers and in natural and acquired immunity. In the COVID-19 pandemic, the strength of personal immunity is very important in the severe or lightening of the disease, even if there are variants of the virus or if you are vaccinated. Methods: In this study, we investigated the relationship between the clinical course and vitamin D levels of outpatient and inpatient follow-up patients admitted to our hospital due to COVID-19. A total of 94 patients, 47 outpatients and 47 inpatients, were included in the study. Result: The mean age and gender distributions of both groups were similar. Vitamin D levels were found to be normal in only 7 of 94 patients who were followed up in our hospital due to COVID-19. Patients with vitamin D levels 30 were significantly lower than those with 10 and 10-29.9 p0.01 for each. Hospitalized patients 71 with vitamin D levels 10 were significantly higher than those 0 with vitamin D levels 30. Additionally, the outpatients 29 with vitamin D levels 10 were significantly lower than those 100 with vitamin D levels 30. Conclusion: We showed that vitamin D deficiency may be associated with the severe clinical course of COVID-19, even in patients without comorbidities, and may also be one of the predisposing factors resulting in death in COVID-19. The data suggest that it is crucial to continue vitamin D supplements during the COVID-19 pandemic.

 Amaç: Vitamin D, mukozal bariyerlerin bütünlüğünün korunmasında, doğal ve kazanılmış bağışıklıkta önemli rol oynar. COVID-19 pandemisinde, virüsün varyantları olsa veya aşılanmış olsanız bile, hastalığın ağırlaşmasında veya hafifletilmesinde kişisel bağışıklığın gücü çok önemlidir. Gereç ve Yöntem: Bu çalışmada hastanemize COVID-19 nedeniyle başvuran ayaktan ve yatarak tedavi gören hastaların klinik seyri ile D vitamini düzeyleri arasındaki ilişkiyi araştırdık. 47 ayaktan ve 47 yatan hasta olmak üzere toplam 94 hasta çalışmaya dahil edildi. Bulgular: Her iki grubun ortalama yaş ve cinsiyet dağılımları benzerdi. Hastanemizde COVID-19 nedeniyle takip edilen 94 hastanın sadece 7sinde D vitamini seviyeleri normal bulundu. D vitamini düzeyi 30 olan hastalar, 10 ve 10-29.9 olanlardan anlamlı derecede düşüktü her biri için p0.01. D vitamini düzeyi 10 olan hastanede yatan hastalar 71, D vitamini düzeyi 30 olanlardan 0 anlamlı olarak daha yüksekti. Ek olarak, D vitamini düzeyi 10 olan ayaktan hastalar 29, D vitamini düzeyi 30 olanlardan 100 anlamlı olarak daha düşüktü. Sonuç: D vitamini eksikliğinin komorbiditesi olmayan hastalarda bile COVID-19un şiddetli klinik seyri ile ilişkili olabileceğini ve ayrıca COVID-19da ölümle sonuçlanan predispozan faktörlerden biri olabileceğini gösterdik. Veriler, COVID-19 salgını sırasında D vitamini takviyelerine devam etmenin çok önemli olduğunu gösteriyor.

Article Details

The Effect of Vitamin D Level on the Clinical Situation in COVID-19 Patients

Authors:

Fatih Davran | Ceyhan Hacıoğlu | Eda Kayabaşı | Banu Hümeyra Keskin | Pelin Duran | Elif Nisa Unlu | Elif Eşcan | Şengül Cangür | Cihadiye Elif Öztürk

Publisher:

Duzce University

Main Topics:

Health Care Administration

Journal:

Konuralp Medical Journal Vol.15 Issue 1, pp.130-135

Document Type:

Article

Publication Date:

3/2023

Document Language:

English

Document ID (Org No.):

2001285278

pISSN:

1309-3878

Vitamin D

COVID-19

clinical course

inpatients

outpatients

D vitamini

COVID-19

klinik seyir

yatan hastalar

ayaktan hastalar

Issues

Article Details

Authors: Fatih Davran | Ceyhan Hacıoğlu | Eda Kayabaşı | Banu Hümeyra Keskin | Pelin Duran | Elif Nisa Unlu | Elif Eşcan | Şengül Cangür | Cihadiye Elif Öztürk

Publisher: Duzce University

Main Topics: Health Care Administration

Journal: Konuralp Medical Journal Vol.15 Issue 1, pp.130-135

Document Type: Article

Publication Date: 3/2023

Document Language: English

Document ID (Org No.): 2001285278

pISSN: 1309-3878

Issues

Authors:

Fatih Davran | Ceyhan Hacıoğlu | Eda Kayabaşı | Banu Hümeyra Keskin | Pelin Duran | Elif Nisa Unlu | Elif Eşcan | Şengül Cangür | Cihadiye Elif Öztürk

Publisher:

Duzce University

Main Topics:

Health Care Administration

Journal:

Konuralp Medical Journal Vol.15 Issue 1, pp.130-135

Document Type:

Article

Publication Date:

3/2023

Document Language:

English

Document ID (Org No.):

2001285278

pISSN:

1309-3878