Prevalence of Thrombocytopenia in Egyptian Patients with Chronic Hepatitis C Virus

Sayed Farouk Mohamed

doi:10.12816/0006419

Article Details

Prevalence of Thrombocytopenia in Egyptian Patients with Chronic Hepatitis C Virus

Authors:

Sayed Farouk Mohamed

Publisher:

The Egyptian Society of Parasitology

Main Topics:

Medicine

Journal:

Journal of the Egyptian Society of Parasitology 2013 Vol.43 Issue 3, pp.617-628

Document Type:

Article

Publication Date:

12/2013

Document Language:

English

Document ID (Org No.):

53569

Frequency:

Tri-Annual

pISSN:

11100583

DOI:

10.12816/0006419

Descriptors:

Keywords:

Abstract:

 Thrombocytopenia is defined as a platelet count less than 150.000/mm3. It is acommon finding in subjects with chronic hepatitis as HCV antibody-positive individualsare 2.6 times more likely to have a low platelet count than those who areHCV-antibody negative. However, controversy still exists concerning the mechanismof HCV-associated thrombocytopeniaThis work studied the thrombocytopenia prevalence in Egyptian patients withchronic HCV. Data of 100 patients with chronic hepatitis C presented to TropicalMedicine department, Al-Azhar University, included full history, clinical assessment,laboratory investigations (complete blood count, liver biochemical profile,kidney function tests and PCR), abdominal ultrasound and liver biopsy.The prevalence of thrombocytopenia among patients was 24/100 (24%), mildthrombocytopenia was the commonest grade (17%) then moderate one (6%) andlastly severe thrombocytopenia (1%). Thrombocytopenia significantly occurredmore in older ages with high AST and ALT levels. The prevalence of thrombocytopeniasignificantly increased with abnormality liver Echopattern and with theprogress of fibrosis and activity in liver biopsy.

Article Details

Prevalence of Thrombocytopenia in Egyptian Patients with Chronic Hepatitis C Virus

Authors:

Sayed Farouk Mohamed

Publisher:

The Egyptian Society of Parasitology

Main Topics:

Medicine

Journal:

Journal of the Egyptian Society of Parasitology 2013 Vol.43 Issue 3, pp.617-628

Document Type:

Article

Publication Date:

12/2013

Document Language:

English

Document ID (Org No.):

53569

Frequency:

Tri-Annual

pISSN:

11100583

DOI:

10.12816/0006419

Descriptors:

THROMBOCYTOPENIA

HEPATITIS

ANTIBODIES

BIOCHEMICALS

PATIENTS

EGYPT

Egyptian Patients

Thrombocytopenia

Chronic HCV

Issues

Article Details

Authors: Sayed Farouk Mohamed

Publisher: The Egyptian Society of Parasitology

Main Topics: Medicine

Journal: Journal of the Egyptian Society of Parasitology 2013 Vol.43 Issue 3, pp.617-628

Document Type: Article

Publication Date: 12/2013

Document Language: English

Document ID (Org No.): 53569

Frequency: Tri-Annual

pISSN: 11100583

DOI: 10.12816/0006419

Descriptors:

Issues

Authors:

Sayed Farouk Mohamed

Publisher:

The Egyptian Society of Parasitology

Main Topics:

Medicine

Journal:

Journal of the Egyptian Society of Parasitology 2013 Vol.43 Issue 3, pp.617-628

Document Type:

Article

Publication Date:

12/2013

Document Language:

English

Document ID (Org No.):

53569

Frequency:

Tri-Annual

pISSN:

11100583

DOI:

10.12816/0006419