Effects of Exposure to Total Particulate Matter of Cashew Nuts Shell in the Respiratory System of Mice with Chronic Obstructive Pulmonary Disease

Fladimir de Lima Gondim; Gilvan Ribeiro dos Santos; Daniel Silveira Serra; Rinaldo dos Santos Araújo; Mona Lisa Moura de Oliveira; Francisco Sales Aacute; vila Cavalcante

Article Details

Effects of Exposure to Total Particulate Matter of Cashew Nuts Shell in the Respiratory System of Mice with Chronic Obstructive Pulmonary Disease

Authors:

Fladimir de Lima Gondim | Gilvan Ribeiro dos Santos | Daniel Silveira Serra | Rinaldo dos Santos Araújo | Mona Lisa Moura de Oliveira | Francisco Sales Aacute | vila Cavalcante

Publisher:

AENSI (American-Eurasian Network for Scientific Information)

Journal:

Australian Journal of Basic and Applied Sciences Vol.13 Issue 1, pp.71-79

Document Type:

Article

Publication Date:

1/2019

Document Language:

English

Document ID (Org No.):

2001857951

pISSN:

1991-8178

Abstract:

 About 3 billion people are exposed to biomass fuel smoke compared to 1.1 billion people who smoke tobacco, suggesting that exposure to biomass smoke may be the most important global risk factor for Chronic obstructive pulmonary diseases COPD. Due to the increasing use of residual biomass as an energy source, there is a need to investigate the effects of exposure to total particulate matter from combustion exhaust gases from cashew nut shells (CNS) in more susceptible population groups. Thus, in the present study, we sought to investigate the effects of exposure to TPM of SNC in the Respiratory System of mice with COPD. To perform this investigation, C57black/6 mice were exposed to cigarette smoke or ambient air (CTRL group) for 60 days, and after this period the animals were submitted to 20 days of nasal instillation containing TPM (CS+TPM) or saline solution (CS). 24 h after last instillation, the animals were connected to a ventilator for small animals to perform the analyzes referring to the variables of the respiratory system mechanics. Our results demonstrated changes in all variables analyzed between the CS+TPM, CS and CTRL groups, and there was greater hyperresponsiveness in smooth muscle of the airways, demonstrating that the lung injury of animals caused by exposure to cigarette smoke is greater when associated with exposure to TMP from CNS combustion. In this way, increasing use of this biofuel in industries, craft centers and residences, can be can be harmful, especially to those with pre-existing respiratory disease. [.

Article Details

Effects of Exposure to Total Particulate Matter of Cashew Nuts Shell in the Respiratory System of Mice with Chronic Obstructive Pulmonary Disease

Authors: Fladimir de Lima Gondim | Gilvan Ribeiro dos Santos | Daniel Silveira Serra | Rinaldo dos Santos Araújo | Mona Lisa Moura de Oliveira | Francisco Sales Aacute | vila Cavalcante

Publisher: AENSI (American-Eurasian Network for Scientific Information)

Journal: Australian Journal of Basic and Applied Sciences Vol.13 Issue 1, pp.71-79

Document Type: Article

Publication Date: 1/2019

Document Language: English

Document ID (Org No.): 2001857951

pISSN: 1991-8178

Issues

Authors:

Fladimir de Lima Gondim | Gilvan Ribeiro dos Santos | Daniel Silveira Serra | Rinaldo dos Santos Araújo | Mona Lisa Moura de Oliveira | Francisco Sales Aacute | vila Cavalcante

Publisher:

AENSI (American-Eurasian Network for Scientific Information)

Journal:

Australian Journal of Basic and Applied Sciences Vol.13 Issue 1, pp.71-79

Document Type:

Article

Publication Date:

1/2019

Document Language:

English

Document ID (Org No.):

2001857951

pISSN:

1991-8178