A comparative study of preoperative versus intraoperative meperidine administration in patients receiving general anesthesia: a prospective, randomized double-blind study

Hüseyin SERT; Rüveyda İrem DEMİRCİOĞLU; Burhanettin USTA; Bünyamin MUSLU; Ümmügülsüm YAZICI; Muhammet GÖZDEMİR; Önder SÜRGİT

Article Details

A comparative study of preoperative versus intraoperative meperidine administration in patients receiving general anesthesia: a prospective, randomized double-blind study

Authors:

Hüseyin SERT | Rüveyda İrem DEMİRCİOĞLU | Burhanettin USTA | Bünyamin MUSLU | Ümmügülsüm YAZICI | Muhammet GÖZDEMİR | Önder SÜRGİT

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2012 Vol.42 Issue 1, pp.47-54

Document Type:

Article

Publication Date:

12/2011

Document Language:

Turkish

Document ID (Org No.):

2000754281

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Keywords:

Abstract:

 

To evaluate the effects of preoperative and intraoperative administration of intravenous meperidine as a preemptive analgesic.  Materials and methods: A total of 50 patients were randomly divided into 2 groups; group P received 1 mg/kg of meperidine intravenously immediately before induction of anesthesia, and group I received the same amount of meperidine 20 min before completion of surgery. Consumption of desflurane, recovery parameters, heart rate, mean arterial pressure, sedation scores, visual analog scale (VAS) scores for pain, analgesic needs, and anesthesia-related complications were recorded for both groups.   Results: Time to recovery was significantly shorter in group P than in group I for all parameters except spontaneous respiration. The postoperative sedation scores were mostly similar for the 2 groups, with the exception of the number of patients with postoperative 60-min sedation scores of 2; this score was seen in 1 patient in group P and 7 patients in group I. The VAS scores of group I in the postoperative period were higher than those of group P.   Conclusion: Preoperative meperidine administration shows superiority to intraoperative administration with regard to recovery parameters and early postoperative pain scores, but there were no significant differences between the groups with regard to other intraoperative and postoperative parameters.

 

To evaluate the effects of preoperative and intraoperative administration of intravenous meperidine as a preemptive analgesic.  Materials and methods: A total of 50 patients were randomly divided into 2 groups; group P received 1 mg/kg of meperidine intravenously immediately before induction of anesthesia, and group I received the same amount of meperidine 20 min before completion of surgery. Consumption of desflurane, recovery parameters, heart rate, mean arterial pressure, sedation scores, visual analog scale (VAS) scores for pain, analgesic needs, and anesthesia-related complications were recorded for both groups.   Results: Time to recovery was significantly shorter in group P than in group I for all parameters except spontaneous respiration. The postoperative sedation scores were mostly similar for the 2 groups, with the exception of the number of patients with postoperative 60-min sedation scores of 2; this score was seen in 1 patient in group P and 7 patients in group I. The VAS scores of group I in the postoperative period were higher than those of group P.   Conclusion: Preoperative meperidine administration shows superiority to intraoperative administration with regard to recovery parameters and early postoperative pain scores, but there were no significant differences between the groups with regard to other intraoperative and postoperative parameters.

Article Details

A comparative study of preoperative versus intraoperative meperidine administration in patients receiving general anesthesia: a prospective, randomized double-blind study

Authors:

Hüseyin SERT | Rüveyda İrem DEMİRCİOĞLU | Burhanettin USTA | Bünyamin MUSLU | Ümmügülsüm YAZICI | Muhammet GÖZDEMİR | Önder SÜRGİT

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2012 Vol.42 Issue 1, pp.47-54

Document Type:

Article

Publication Date:

12/2011

Document Language:

Turkish

Document ID (Org No.):

2000754281

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Key words: Desflurane consumption

meperidine

postoperative pain

preemptive analgesia

recovery

Issues

Article Details

A comparative study of preoperative versus intraoperative meperidine administration in patients receiving general anesthesia: a prospective, randomized double-blind study

Authors: Hüseyin SERT | Rüveyda İrem DEMİRCİOĞLU | Burhanettin USTA | Bünyamin MUSLU | Ümmügülsüm YAZICI | Muhammet GÖZDEMİR | Önder SÜRGİT

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2012 Vol.42 Issue 1, pp.47-54

Document Type: Article

Publication Date: 12/2011

Document Language: Turkish

Document ID (Org No.): 2000754281

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Key words: Desflurane consumption

meperidine

postoperative pain

preemptive analgesia

recovery

Issues

Authors:

Hüseyin SERT | Rüveyda İrem DEMİRCİOĞLU | Burhanettin USTA | Bünyamin MUSLU | Ümmügülsüm YAZICI | Muhammet GÖZDEMİR | Önder SÜRGİT

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2012 Vol.42 Issue 1, pp.47-54

Document Type:

Article

Publication Date:

12/2011

Document Language:

Turkish

Document ID (Org No.):

2000754281

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144