Evaluation of inappropriate drug use in geriatric patients using the TIME-to-STOP/TIME-to-START criteria in a tertiary hospital

Ajla Hodzıc; Berna Terzioğlu Bebitoğlu; Elif Oğuz; Banu Mesci

Article Details

Evaluation of inappropriate drug use in geriatric patients using the TIME-to-STOP/TIME-to-START criteria in a tertiary hospital

Authors:

Ajla Hodzıc | Berna Terzioğlu Bebitoğlu | Elif Oğuz | Banu Mesci

Publisher:

Marmara University

Main Topics:

Medical Pharmacology

Journal:

Journal of Research in Pharmacy Vol.27 Issue 2, pp.687-695

Document Type:

Article

Publication Date:

6/2025

Document Language:

English

Document ID (Org No.):

2001347832

pISSN:

2630-6344

Keywords:

Abstract:

 This study aimed to determine the frequency and factors affecting inappropriate drug use and polypharmacy in geriatric patients. The data on 318 geriatric patients hospitalized between January 1, 2020, and July 1, 2020, in the internal medicine clinic of a tertiary hospital were analyzed retrospectively. Inappropriate drug use was evaluated according to the Turkish Inappropriate Medication Use in the Elderly TIME TIME-to-STOP TIME-to- START criteria. Of the 318 patients, 157 49.4 used at least one potentially inappropriate drug. The most frequently used inappropriate drugs according to TIME-to-START criteria were related to B the central nervous system n  28; 53.89, A the cardiovascular system n  26; 33.33, and I supplements n  24; 30.77. The most frequently used inappropriate drugs according to TIME-to-STOP criteria were related to B the central nervous system n  258; 45.18, C the gastrointestinal system n  224; 39.23, and D the respiratory system n  44; 7.71. A total of 225 70.8 patients engaged in polypharmacy at least once. Conclusion: There is a high rate of potentially inappropriate drug use and polypharmacy among Turkish geriatric patients. The use of published guidelines should be expanded in Turkey.

 This study aimed to determine the frequency and factors affecting inappropriate drug use and polypharmacy in geriatric patients. The data on 318 geriatric patients hospitalized between January 1, 2020, and July 1, 2020, in the internal medicine clinic of a tertiary hospital were analyzed retrospectively. Inappropriate drug use was evaluated according to the Turkish Inappropriate Medication Use in the Elderly TIME TIME-to-STOP TIME-to- START criteria. Of the 318 patients, 157 49.4 used at least one potentially inappropriate drug. The most frequently used inappropriate drugs according to TIME-to-START criteria were related to B the central nervous system n  28; 53.89, A the cardiovascular system n  26; 33.33, and I supplements n  24; 30.77. The most frequently used inappropriate drugs according to TIME-to-STOP criteria were related to B the central nervous system n  258; 45.18, C the gastrointestinal system n  224; 39.23, and D the respiratory system n  44; 7.71. A total of 225 70.8 patients engaged in polypharmacy at least once. Conclusion: There is a high rate of potentially inappropriate drug use and polypharmacy among Turkish geriatric patients. The use of published guidelines should be expanded in Turkey.

 This study aimed to determine the frequency and factors affecting inappropriate drug use and polypharmacy in geriatric patients. The data on 318 geriatric patients hospitalized between January 1, 2020, and July 1, 2020, in the internal medicine clinic of a tertiary hospital were analyzed retrospectively. Inappropriate drug use was evaluated according to the Turkish Inappropriate Medication Use in the Elderly TIME TIME-to-STOP TIME-to- START criteria. Of the 318 patients, 157 49.4 used at least one potentially inappropriate drug. The most frequently used inappropriate drugs according to TIME-to-START criteria were related to B the central nervous system n  28; 53.89, A the cardiovascular system n  26; 33.33, and I supplements n  24; 30.77. The most frequently used inappropriate drugs according to TIME-to-STOP criteria were related to B the central nervous system n  258; 45.18, C the gastrointestinal system n  224; 39.23, and D the respiratory system n  44; 7.71. A total of 225 70.8 patients engaged in polypharmacy at least once. Conclusion: There is a high rate of potentially inappropriate drug use and polypharmacy among Turkish geriatric patients. The use of published guidelines should be expanded in Turkey.

 This study aimed to determine the frequency and factors affecting inappropriate drug use and polypharmacy in geriatric patients. The data on 318 geriatric patients hospitalized between January 1, 2020, and July 1, 2020, in the internal medicine clinic of a tertiary hospital were analyzed retrospectively. Inappropriate drug use was evaluated according to the Turkish Inappropriate Medication Use in the Elderly TIME TIME-to-STOP TIME-to- START criteria. Of the 318 patients, 157 49.4 used at least one potentially inappropriate drug. The most frequently used inappropriate drugs according to TIME-to-START criteria were related to B the central nervous system n  28; 53.89, A the cardiovascular system n  26; 33.33, and I supplements n  24; 30.77. The most frequently used inappropriate drugs according to TIME-to-STOP criteria were related to B the central nervous system n  258; 45.18, C the gastrointestinal system n  224; 39.23, and D the respiratory system n  44; 7.71. A total of 225 70.8 patients engaged in polypharmacy at least once. Conclusion: There is a high rate of potentially inappropriate drug use and polypharmacy among Turkish geriatric patients. The use of published guidelines should be expanded in Turkey.

Article Details

Evaluation of inappropriate drug use in geriatric patients using the TIME-to-STOP/TIME-to-START criteria in a tertiary hospital

Authors:

Ajla Hodzıc | Berna Terzioğlu Bebitoğlu | Elif Oğuz | Banu Mesci

Publisher:

Marmara University

Main Topics:

Medical Pharmacology

Journal:

Journal of Research in Pharmacy Vol.27 Issue 2, pp.687-695

Document Type:

Article

Publication Date:

6/2025

Document Language:

English

Document ID (Org No.):

2001347832

pISSN:

2630-6344

inappropriate drug use

geriatrics

polypharmacy

prescribing

Issues

Article Details

Evaluation of inappropriate drug use in geriatric patients using the TIME-to-STOP/TIME-to-START criteria in a tertiary hospital

Authors: Ajla Hodzıc | Berna Terzioğlu Bebitoğlu | Elif Oğuz | Banu Mesci

Publisher: Marmara University

Main Topics: Medical Pharmacology

Journal: Journal of Research in Pharmacy Vol.27 Issue 2, pp.687-695

Document Type: Article

Publication Date: 6/2025

Document Language: English

Document ID (Org No.): 2001347832

pISSN: 2630-6344

inappropriate drug use

geriatrics

polypharmacy

prescribing

Issues

Authors:

Ajla Hodzıc | Berna Terzioğlu Bebitoğlu | Elif Oğuz | Banu Mesci

Publisher:

Marmara University

Main Topics:

Medical Pharmacology

Journal:

Journal of Research in Pharmacy Vol.27 Issue 2, pp.687-695

Document Type:

Article

Publication Date:

6/2025

Document Language:

English

Document ID (Org No.):

2001347832

pISSN:

2630-6344