Thyroid Diseases and Treatment in Pregnancy

Aynur AKTAŞ; Zafer PEKKOLAY

doi:https://doi.org/10.5799/jcei.328705

Article Details

Thyroid Diseases and Treatment in Pregnancy

Authors:

Aynur AKTAŞ | Zafer PEKKOLAY

Publisher:

Sağlık Araştırmaları Derneği

Main Topics:

Promotion of health

Journal:

Journal of Clinical and Experimental Investigations 2016 Vol.7 Issue 1, pp.119-123

Document Type:

Article

Publication Date:

2/2016

Document Language:

Turkish

Document ID (Org No.):

2000833275

Frequency:

Quarterly

eISSN:

1309-6621

pISSN:

1309-8578

DOI:

https://doi.org/10.5799/jcei.328705

Abstract:

 


Assessment of thyroid disease in pregnancy is important for gestational maternal health, obstetric outcome and, subsequent
development of child. Pregnancy has profound effects on the regulation of thyroid function, and on thyroidal
functional disorders, that need to be recognized, carefully evaluated and correctly managed. In women with normal
thyroid function there is an increase in thyroxine (T4) and triiodothyronine (T3) production and inhibition of thyroidstimulating
hormone (TSH) in the first trimester of pregnancy,. In the pregnant woman, elevated thyroxine-binding
globulin (TGB) and concomitant increases in total T4 and T3 levels plateau at 12-14 weeks of pregnancy, and free T4
measurements slowly decrease. The most frequent thyroid disorder in pregnancy is maternal hypothyroidism. It is associated
with fetal loss, placental abruptions, preeclampsia, preterm delivery and reduced intellectual function in the
offspring. Hyperthyroidism during pregnancy is relatively uncommon, with a prevalence estimated to range between
0.1% and 1%. The most common cause of hyperthyroidism is Graves disease, as this etiology accounts for 85% of clinical
hyperthyroidism in pregnancy. Another cause of hyperthyroidism is hyperemesis gravidarum. This is common and
requires differentiation from Graves disease. There has been much discussion and many publications on the optimal
management of pregnant women who are hyperthyroid or hypothyroid. Despite the lack of consensus organizations,
which are based on analyses, support screening in all pregnant women in the first trimester for thyroid disease. In this
article, we provide information about the current approaches of thyroid dysfunction in pregnancy. J Clin Exp Invest 2016;
7 (1): 119-123.

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Article Details

Thyroid Diseases and Treatment in Pregnancy

Authors: Aynur AKTAŞ | Zafer PEKKOLAY

Publisher: Sağlık Araştırmaları Derneği

Main Topics: Promotion of health

Journal: Journal of Clinical and Experimental Investigations 2016 Vol.7 Issue 1, pp.119-123

Document Type: Article

Publication Date: 2/2016

Document Language: Turkish

Document ID (Org No.): 2000833275

Frequency: Quarterly

eISSN: 1309-6621

pISSN: 1309-8578

DOI: https://doi.org/10.5799/jcei.328705

Issues

Authors:

Aynur AKTAŞ | Zafer PEKKOLAY

Publisher:

Sağlık Araştırmaları Derneği

Main Topics:

Promotion of health

Journal:

Journal of Clinical and Experimental Investigations 2016 Vol.7 Issue 1, pp.119-123

Document Type:

Article

Publication Date:

2/2016

Document Language:

Turkish

Document ID (Org No.):

2000833275

Frequency:

Quarterly

eISSN:

1309-6621

pISSN:

1309-8578

DOI:

https://doi.org/10.5799/jcei.328705