Surgical Approaches in Refractory Obsessive Compulsive Disorder: From Leukotomy to Gamma Knife Surgery

Ebru ALTINTAŞ

doi:https://doi.org/10.17827/aktd.29712

Article Details

Surgical Approaches in Refractory Obsessive Compulsive Disorder: From Leukotomy to Gamma Knife Surgery

Authors:

Ebru ALTINTAŞ

Publisher:

Cukurova University

Journal:

Archives Medical Review Journal 2015 Vol.24 Issue 2, pp.239-250

Document Type:

Article

Publication Date:

3/2015

Document Language:

English

Document ID (Org No.):

2000862804

Frequency:

Quarterly

eISSN:

2602-3024

pISSN:

1300-3755

DOI:

https://doi.org/10.17827/aktd.29712

Keywords:

Abstract:

 

Obsessive Compulsive Disorder (OCD) is a chronic and debilitating disorder that can cause significant distress and interference with daily functioning and impairment in quality of life, social and familial relationship. Selective serotonin reuptake inhibitors and cognitive-behavioral therapy are currently viewed as the first line treatments of choice for OCD. Approximately 30-40% OCD patients fail to respond to these treatments. Anterior capsulotomy, cingulotomy, limbic leucotomy, subcaudate tractotomy are used for the treatment of refractory OCD. The studies suggested that gamma knife capsulotomy caused improvements in 55-70% refractory OCD patients. Many studies suggest that psychosurgery is a beneficial, well tolerated and safe method. This study aimed to report efficacy, adverse effects and long term effects of surgery techniques especially gamma knife and deep brain stimulation in refractory OCD patients .

 

Obsesif Kompulsif Bozukluk(OKB) obsesyon ve kompulsiyonlarla karakterize yaygın bir ruhsal bozukluktur. Obsesif Kompulsif Bozukluk, sosyal, ailesel ilişkiler, yaşam kalitesi ve günlük işlevlerde bozulma yapan, önemli derecede strese yol açan kronik ve zayıf düşürücü bir hastalıktır. Selektif seratonin geri alım inhibitörleri ve bilişsel davranışçı terapi, OKB’nin tedavisinde ilk tercih yöntemleridir. Yaklaşık olarak %30-40 OKB hastası bu tedaviye yanıt vermez. Anterior kapsülotomi, singulotomi, subkaudat traktotomi, limbik lökotomi dirençli OKB’nin cerrahi tedavisinde kullanılabilir. Araştırmalar, gama kapsulotominin %55-70 dirençli OKB hastasında düzelme sağladığını göstermiştir. Literatürde, psikiyatrik cerrahinin faydalı, iyi tolere edilen ve güvenilir bir yöntem olduğu bazı araştırmalarda sunulmuştur. Bu derlemenin amacı, tedaviye dirençli OKB hastalarında kullanılan cerrahi yöntemlerin özellikle gama bıçağı kapsülotomi ve derin beyin stimülasyonunun etkinliği, yan etkileri ve uzun dönem etkilerini sunmaktır.

Article Details

Surgical Approaches in Refractory Obsessive Compulsive Disorder: From Leukotomy to Gamma Knife Surgery

Authors:

Ebru ALTINTAŞ

Publisher:

Cukurova University

Journal:

Archives Medical Review Journal 2015 Vol.24 Issue 2, pp.239-250

Document Type:

Article

Publication Date:

3/2015

Document Language:

English

Document ID (Org No.):

2000862804

Frequency:

Quarterly

eISSN:

2602-3024

pISSN:

1300-3755

DOI:

https://doi.org/10.17827/aktd.29712

Obsesif-kompulsif bozukluk

kapsülotomi

gama bıçağı

derin beyin stimülasyonu

Issues

Article Details

Surgical Approaches in Refractory Obsessive Compulsive Disorder: From Leukotomy to Gamma Knife Surgery

Authors: Ebru ALTINTAŞ

Publisher: Cukurova University

Journal: Archives Medical Review Journal 2015 Vol.24 Issue 2, pp.239-250

Document Type: Article

Publication Date: 3/2015

Document Language: English

Document ID (Org No.): 2000862804

Frequency: Quarterly

eISSN: 2602-3024

pISSN: 1300-3755

DOI: https://doi.org/10.17827/aktd.29712

Obsesif-kompulsif bozukluk

kapsülotomi

gama bıçağı

derin beyin stimülasyonu

Issues

Authors:

Ebru ALTINTAŞ

Publisher:

Cukurova University

Journal:

Archives Medical Review Journal 2015 Vol.24 Issue 2, pp.239-250

Document Type:

Article

Publication Date:

3/2015

Document Language:

English

Document ID (Org No.):

2000862804

Frequency:

Quarterly

eISSN:

2602-3024

pISSN:

1300-3755

DOI:

https://doi.org/10.17827/aktd.29712