Synthesis and Characterization of Novel Compounds Containing of Imidazolidinone and Oxazepine Rings

T. R. Muhsen; J. H. Tomma; A. J. A. Mukhlus

Article Details

Synthesis and Characterization of Novel Compounds Containing of Imidazolidinone and Oxazepine Rings

Authors:

T. R. Muhsen | J. H. Tomma | A. J. A. Mukhlus

Publisher:

University of Baghdad

Journal:

Ibn AL-Haitham Journal For Pure and Applied Sciences Vol.25 Issue 3, pp.276-283

Document Type:

Article

Publication Date:

1/2012

Document Language:

English

Document ID (Org No.):

2001377033

pISSN:

2521-3407

Keywords:

Abstract:

 The compound 3-[4Ì„-(4Ë-methoxy benzoyloxy) benzylideneamino]-2-thioxo-imidazolidine-4-one [III] was prepared from the cyclization of thiosemicarbazone [II] with ethyl Î± -chloroacetate in the presence of fused sodium acetate. Treatment the later compound with acetic anhydride yielded the corresponding 1-Acetyl-3-[ 4Ì„- (4Ë- methoxy benzoyloxy) benzylideneamino] â€“ 2 â€“ thioxo -imidazolidine-4-one [IV]. 1,3-Oxazepine derivatives [V]a-dand [VI]a-d are obtained from the reaction of compounds[III] and [IV] with different acid anhydrides, in dry benzene. The FTIR and1HNMR spectroscopy are indicated a good evidence for the formation of the synthesized compounds. Some of the synthesized compounds have been screened against E.coli , Staph. aureus , Psenudomonsaeruginosa and Bascillus cereus . They exhibited moderate to weak antibacterial activity unless compound [V]d did not show any biological activity.

Article Details

Synthesis and Characterization of Novel Compounds Containing of Imidazolidinone and Oxazepine Rings

Authors:

T. R. Muhsen | J. H. Tomma | A. J. A. Mukhlus

Publisher:

University of Baghdad

Journal:

Ibn AL-Haitham Journal For Pure and Applied Sciences Vol.25 Issue 3, pp.276-283

Document Type:

Article

Publication Date:

1/2012

Document Language:

English

Document ID (Org No.):

2001377033

pISSN:

2521-3407

imidazolidenone

oxazepine

Issues

Article Details

Synthesis and Characterization of Novel Compounds Containing of Imidazolidinone and Oxazepine Rings

Authors: T. R. Muhsen | J. H. Tomma | A. J. A. Mukhlus

Publisher: University of Baghdad

Journal: Ibn AL-Haitham Journal For Pure and Applied Sciences Vol.25 Issue 3, pp.276-283

Document Type: Article

Publication Date: 1/2012

Document Language: English

Document ID (Org No.): 2001377033

pISSN: 2521-3407

imidazolidenone

oxazepine

Issues

Authors:

T. R. Muhsen | J. H. Tomma | A. J. A. Mukhlus

Publisher:

University of Baghdad

Journal:

Ibn AL-Haitham Journal For Pure and Applied Sciences Vol.25 Issue 3, pp.276-283

Document Type:

Article

Publication Date:

1/2012

Document Language:

English

Document ID (Org No.):

2001377033

pISSN:

2521-3407