Predisposing role of heterozygote MTHFR A1298C  mutation in venous thrombosis in a pregnant patient: A case report

Ayse Arduc; Serhat Isik; Berçem Aycicek Dogan; Ufuk Ozuguz; Gulhan Akbaba; Dilek Berker; Serdar Guler

Article Details

Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report

Authors:

Ayse Arduc | Serhat Isik | Berçem Aycicek Dogan | Ufuk Ozuguz | Gulhan Akbaba | Dilek Berker | Serdar Guler

Publisher:

Eldaghayes Publisher, Tripoli, Libya

Main Topics:

Pregnancy | MTHFR A1298C mutation | Venous thrombosis

Journal:

International Journal of Medical Science and Public Health Vol.2 Issue 1, pp.159-159

Document Type:

Article

Publication Date:

11/2012

Document Language:

English

Document ID (Org No.):

2001520778

pISSN:

2320-4664

Keywords:

Abstract:

 Congenital and acquired thrombophilia are associated with an increased risk of pregnancy-associated venous thrombosis (VT). Several genetic mechanisms have been investigated for their possible relationship with VT. Methyl tetrahydrofolate reductase gene polymorphisms are frequently in the MTHFR gene, which leads to a C to T change at position 677, has been suggested to alter the thrombohemostasis process and thrombophilia (1). Also, it has been found that MTHFR C1298C or MTHFR A1298C have no effect on the risk of VT (1). Herein, we describe deep VT (DVT) secondary to heterozygous MTHFR A1298C mutation in pregnant woman.

Article Details

Predisposing role of heterozygote MTHFR A1298C mutation in venous thrombosis in a pregnant patient: A case report

Authors: Ayse Arduc | Serhat Isik | Berçem Aycicek Dogan | Ufuk Ozuguz | Gulhan Akbaba | Dilek Berker | Serdar Guler

Publisher: Eldaghayes Publisher, Tripoli, Libya

Main Topics: Pregnancy | MTHFR A1298C mutation | Venous thrombosis

Journal: International Journal of Medical Science and Public Health Vol.2 Issue 1, pp.159-159

Document Type: Article

Publication Date: 11/2012

Document Language: English

Document ID (Org No.): 2001520778

pISSN: 2320-4664

Pregnancy

MTHFR A1298C mutation

Venous thrombosis

Issues

Authors:

Ayse Arduc | Serhat Isik | Berçem Aycicek Dogan | Ufuk Ozuguz | Gulhan Akbaba | Dilek Berker | Serdar Guler

Publisher:

Eldaghayes Publisher, Tripoli, Libya

Main Topics:

Pregnancy | MTHFR A1298C mutation | Venous thrombosis

Journal:

International Journal of Medical Science and Public Health Vol.2 Issue 1, pp.159-159

Document Type:

Article

Publication Date:

11/2012

Document Language:

English

Document ID (Org No.):

2001520778

pISSN:

2320-4664