Antioxidant and anticholinesterase activities of Heliotropium dolosum, H. lasiocarpum  and H. hirsutissimum growing in Turkey

Songül KARAKAYA; Mehmet KOCA; Ceyda Sibel KILIÇ

doi:https://doi.org/10.18185/erzifbed.530721

Article Details

Antioxidant and anticholinesterase activities of Heliotropium dolosum, H. lasiocarpum and H. hirsutissimum growing in Turkey

Authors:

Songül KARAKAYA | Mehmet KOCA | Ceyda Sibel KILIÇ

Publisher:

Erzincan Binali Yildirim University

Main Topics:

Applied physics

Journal:

Erzincan University Journal of Science and Technology 2019 Vol.12 Issue 3, pp.1381-1391

Document Type:

Article

Publication Date:

12/2019

Document Language:

English

Document ID (Org No.):

2000414732

eISSN:

2149-4584

pISSN:

1307-9085

DOI:

https://doi.org/10.18185/erzifbed.530721

Abstract:

 


Alzheimer's
disease (AD) has encouraged science to find plants or biologic compounds which
can be utilized for prophylaxis of AD. Heliotropium
genus is presented by 16 taxa in Turkey and they contain pyrrolizidine
alkaloids, and certain are known to have antioxidant and anticholinesterase
activities. The paper displays the anticholinesterase and antioxidant
capacities of the aerial parts lyophilized aqueous extracts of H.
dolosum, H. lasiocarpum and H. hirsutissimum. Phenolic
contents and antioxidant activity of examples were determined by
Folin-Ciocalteu's, qualitative/quantitative DPPH and TBA. Anticholinesterase
activity was assessed by Ellman’s method. The total phenolic content of H. lasiocarpum extract was found the
highest (738.39 mg/g), however the total phenolic content of H. dolosum extract was found the lowest
(122.731 mg/g). Every example indicated that antioxidant activity with DPPH
test and H. lasiocarpum presented the
highest activities (69.99 μg/mL). Furthermore, the H. lasiocarpum extract indicated considerable inhibition towards
acetylcholinesterase (5.90%) and butyrylcholinesyterase (24.04%) enzymes. These
findings suggest that these Heliotropium species can be effective for
pharmaceutic products that achieve anticholinesterase and antioxidant
activities.


.

Article Details

Antioxidant and anticholinesterase activities of Heliotropium dolosum, H. lasiocarpum and H. hirsutissimum growing in Turkey

Authors: Songül KARAKAYA | Mehmet KOCA | Ceyda Sibel KILIÇ

Publisher: Erzincan Binali Yildirim University

Main Topics: Applied physics

Journal: Erzincan University Journal of Science and Technology 2019 Vol.12 Issue 3, pp.1381-1391

Document Type: Article

Publication Date: 12/2019

Document Language: English

Document ID (Org No.): 2000414732

eISSN: 2149-4584

pISSN: 1307-9085

DOI: https://doi.org/10.18185/erzifbed.530721

Issues

Authors:

Songül KARAKAYA | Mehmet KOCA | Ceyda Sibel KILIÇ

Publisher:

Erzincan Binali Yildirim University

Main Topics:

Applied physics

Journal:

Erzincan University Journal of Science and Technology 2019 Vol.12 Issue 3, pp.1381-1391

Document Type:

Article

Publication Date:

12/2019

Document Language:

English

Document ID (Org No.):

2000414732

eISSN:

2149-4584

pISSN:

1307-9085

DOI:

https://doi.org/10.18185/erzifbed.530721