Effects of the oil and mucilage from flaxseed (Linum usitatissimum) on gastric lesions induced by ethanol in rats

A Dugani; A Auzzi; F Naas; S Megwez

doi:10.4176/080612

Article Details

Effects of the oil and mucilage from flaxseed (Linum usitatissimum) on gastric lesions induced by ethanol in rats

Authors:

A Dugani | A Auzzi | F Naas | S Megwez

Publisher:

Libyan Journal of Medicine

Journal:

Libyan Journal of Medicine Vol.3 Issue 4, pp.0-0

Document Type:

Article

Publication Date:

1/2008

Document Language:

English

Document ID (Org No.):

2001392498

pISSN:

1819-6357

DOI:

10.4176/080612

Abstract:

 The anti-ulcer activity of the oil and mucilage obtained from flaxseed (Linum usitatissimum) was evaluated in a rat model of ethanol-induced gastric ulcer. Our results show that pretreatment of rats with flaxseed oil and flaxseed mucilage significantly reduced the number and length of gastric ulcers induced by ethanol. Flaxseed oil was more effective than flaxseed mucilage in reducing the number of ulcers. The reduction in ulcer severity (cumulative length in mm) provided by an oral dose of flaxseed oil (5 ml/kg) was more prominent than that obtained by ranitidine (50 mg/kg). This study indicates that both flaxseed oil and flaxseed mucilage can provide a cytoprotective effect against ethanol-induced gastric ulcers in rats. Keywords: gastric ulcer, flaxseed, ethanol Libyan Journal of Medicine Vol. 3 (4) 2008: pp. 15-19.

Article Details

Effects of the oil and mucilage from flaxseed (Linum usitatissimum) on gastric lesions induced by ethanol in rats

Authors: A Dugani | A Auzzi | F Naas | S Megwez

Publisher: Libyan Journal of Medicine

Journal: Libyan Journal of Medicine Vol.3 Issue 4, pp.0-0

Document Type: Article

Publication Date: 1/2008

Document Language: English

Document ID (Org No.): 2001392498

pISSN: 1819-6357

DOI: 10.4176/080612

Issues

Authors:

A Dugani | A Auzzi | F Naas | S Megwez

Publisher:

Libyan Journal of Medicine

Journal:

Libyan Journal of Medicine Vol.3 Issue 4, pp.0-0

Document Type:

Article

Publication Date:

1/2008

Document Language:

English

Document ID (Org No.):

2001392498

pISSN:

1819-6357

DOI:

10.4176/080612