Comparison of the Distribution of C-fos With Primary Afferent Markers

Zafer SOYGÜDER

Article Details

Comparison of the Distribution of C-fos With Primary Afferent Markers

Authors:

Zafer SOYGÜDER

Publisher:

TUBITAK

Journal:

Turkish Journal of Veterinary and Animal Sciences 1999 Vol.23 Issue 5, pp.499-504

Document Type:

Article

Publication Date:

4/1999

Document Language:

Turkish

Document ID (Org No.):

2000771906

Frequency:

Bimonthly

eISSN:

1303-6181

pISSN:

1300-0128

Keywords:

Abstract:

 

The neuropeptides Substance P (SP) and Calcitonin gene related peptide (CGRP) were used as markers for peptidergic  primary afferent fibres. A lectine, Griffonia simplicifolia (Bandeiraea simplicifolia)Isolectin-B4 (GSA I-B4), was used as a marker for non-peptidergic primary afferent fibres. C-Fos immunoreactivity was determined in the spinal cord of rats which had received 100% mustard oil application in the right hind limb. Darkly labelled c-Fos immunoreactive cells were concentrated in laminae I-IIo of the dorsal horn. SP and GSA I-B4 were distributed almost in the same regions. CGRP was more abundant in laminae I-IIo with someimmunoreactive fibres in lamina IIi. These data suggest that a population of peptidergic and non-peptide primary afferents may play an important function in the induction of c-fos by mustard oil.

 

The neuropeptides Substance P (SP) and Calcitonin gene related peptide (CGRP) were used as markers for peptidergic  primary afferent fibres. A lectine, Griffonia simplicifolia (Bandeiraea simplicifolia)Isolectin-B4 (GSA I-B4), was used as a marker for non-peptidergic primary afferent fibres. C-Fos immunoreactivity was determined in the spinal cord of rats which had received 100% mustard oil application in the right hind limb. Darkly labelled c-Fos immunoreactive cells were concentrated in laminae I-IIo of the dorsal horn. SP and GSA I-B4 were distributed almost in the same regions. CGRP was more abundant in laminae I-IIo with someimmunoreactive fibres in lamina IIi. These data suggest that a population of peptidergic and non-peptide primary afferents may play an important function in the induction of c-fos by mustard oil.

Article Details

Comparison of the Distribution of C-fos With Primary Afferent Markers

Authors:

Zafer SOYGÜDER

Publisher:

TUBITAK

Journal:

Turkish Journal of Veterinary and Animal Sciences 1999 Vol.23 Issue 5, pp.499-504

Document Type:

Article

Publication Date:

4/1999

Document Language:

Turkish

Document ID (Org No.):

2000771906

Frequency:

Bimonthly

eISSN:

1303-6181

pISSN:

1300-0128

c-fos

neuropeptides

lectin

primary afferent fibres

spinal cord.

Issues

Article Details

Comparison of the Distribution of C-fos With Primary Afferent Markers

Authors: Zafer SOYGÜDER

Publisher: TUBITAK

Journal: Turkish Journal of Veterinary and Animal Sciences 1999 Vol.23 Issue 5, pp.499-504

Document Type: Article

Publication Date: 4/1999

Document Language: Turkish

Document ID (Org No.): 2000771906

Frequency: Bimonthly

eISSN: 1303-6181

pISSN: 1300-0128

c-fos

neuropeptides

lectin

primary afferent fibres

spinal cord.

Issues

Authors:

Zafer SOYGÜDER

Publisher:

TUBITAK

Journal:

Turkish Journal of Veterinary and Animal Sciences 1999 Vol.23 Issue 5, pp.499-504

Document Type:

Article

Publication Date:

4/1999

Document Language:

Turkish

Document ID (Org No.):

2000771906

Frequency:

Bimonthly

eISSN:

1303-6181

pISSN:

1300-0128