Investigation of the Effects of Smoking on Blood Metabolic Enzyme Activities in Pregnant Individuals

Esra Şentürk; Gülpınar Aslan; Ela Varol; Murat Şentürk; Metin Yıldız

Article Details

Investigation of the Effects of Smoking on Blood Metabolic Enzyme Activities in Pregnant Individuals

Authors:

Esra Şentürk | Gülpınar Aslan | Ela Varol | Murat Şentürk | Metin Yıldız

Publisher:

Gumushane University

Main Topics:

Sağlık Kurumları Yönetimi

Journal:

Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi Vol.13 Issue 1, pp.274-280

Document Type:

Article

Publication Date:

3/2024

Document Language:

Turkish

Document ID (Org No.):

2001313423

pISSN:

2146-9954

Keywords:

Abstract:

 Pregnancy is process that causes many changes in the expectant mother, both biochemically and physiologically. One of the parameters in which biochemical change is most easily observed and interpreted is enzymatic changes. In this study, blood samples were taken from two groups of pregnant and non-pregnant women in Ağrı. These groups were divided into two groups according to their smoking status and some metabolic enzyme levels were compared. In this context, serum carbonic anhydrase CA, erythrocyte CA, serum catalase CAT, erythrocyte CAT, serum acetylcholinesterase AChE and erythrocyte AChE enzyme levels were compared in pregnant and non-pregnant women. Our study consists of 35 pregnant and 54 non-pregnant individuals living in Ağrı. Personal information forms were collected from the individuals participating in our study by filling in face-to-face interviews. 2 cc blood samples were taken from individuals who agreed to participate. Blood samples were centrifuged and serum and blood cells were separated from each other. Statistical analyzes were performed with the GraphPad Prism 9. In this study, it was determined that the average age of the participants was 25 in pregnant individuals and 22 in non-pregnant individuals. It was determined that 83 of the pregnant women did not smoke and 96 didnt have a chronic disease. It was determined that 6.31 of the non-pregnant individuals participating were smokers. According to the data obtained, both serum and cytoplasm results for all three enzymes of smoking women were lower. In the case of pregnancy, all values were decreased except cytoplasm AChE levels.

 Pregnancy is process that causes many changes in the expectant mother, both biochemically and physiologically. One of the parameters in which biochemical change is most easily observed and interpreted is enzymatic changes. In this study, blood samples were taken from two groups of pregnant and non-pregnant women in Ağrı. These groups were divided into two groups according to their smoking status and some metabolic enzyme levels were compared. In this context, serum carbonic anhydrase CA, erythrocyte CA, serum catalase CAT, erythrocyte CAT, serum acetylcholinesterase AChE and erythrocyte AChE enzyme levels were compared in pregnant and non-pregnant women. Our study consists of 35 pregnant and 54 non-pregnant individuals living in Ağrı. Personal information forms were collected from the individuals participating in our study by filling in face-to-face interviews. 2 cc blood samples were taken from individuals who agreed to participate. Blood samples were centrifuged and serum and blood cells were separated from each other. Statistical analyzes were performed with the GraphPad Prism 9. In this study, it was determined that the average age of the participants was 25 in pregnant individuals and 22 in non-pregnant individuals. It was determined that 83 of the pregnant women did not smoke and 96 didnt have a chronic disease. It was determined that 6.31 of the non-pregnant individuals participating were smokers. According to the data obtained, both serum and cytoplasm results for all three enzymes of smoking women were lower. In the case of pregnancy, all values were decreased except cytoplasm AChE levels.

 Pregnancy is process that causes many changes in the expectant mother, both biochemically and physiologically. One of the parameters in which biochemical change is most easily observed and interpreted is enzymatic changes. In this study, blood samples were taken from two groups of pregnant and non-pregnant women in Ağrı. These groups were divided into two groups according to their smoking status and some metabolic enzyme levels were compared. In this context, serum carbonic anhydrase CA, erythrocyte CA, serum catalase CAT, erythrocyte CAT, serum acetylcholinesterase AChE and erythrocyte AChE enzyme levels were compared in pregnant and non-pregnant women. Our study consists of 35 pregnant and 54 non-pregnant individuals living in Ağrı. Personal information forms were collected from the individuals participating in our study by filling in face-to-face interviews. 2 cc blood samples were taken from individuals who agreed to participate. Blood samples were centrifuged and serum and blood cells were separated from each other. Statistical analyzes were performed with the GraphPad Prism 9. In this study, it was determined that the average age of the participants was 25 in pregnant individuals and 22 in non-pregnant individuals. It was determined that 83 of the pregnant women did not smoke and 96 didnt have a chronic disease. It was determined that 6.31 of the non-pregnant individuals participating were smokers. According to the data obtained, both serum and cytoplasm results for all three enzymes of smoking women were lower. In the case of pregnancy, all values were decreased except cytoplasm AChE levels.

 Gebelik süreci hem biyokimyasal hem de fizyolojik olarak anne adayında birçok değişikliğe sebep olan bir süreçtir. Biyokimyasal değişimin en kolay gözlendiği ve yorumlandığı parametrelerden bir tanesi enzimatik değişimlerdir. Bu çalışmada, Ağrıda gebe ve gebe olmayan iki grup kadından kan örnekleri alındı. Bu gruplar sigara içme durumlarına göre ikişer gruba ayrılarak bazı metabolik enzim seviyeleri kıyaslanmıştır. Bu kapsamda kan serum karbonik anhidraz CA, eritrosit CA, kan serum katalaz CAT, eritrosit CAT, kan serum asetilkolinesteraz AChE ve eritrosit AChE enzim düzeylerinin gebelerde ve gebe olmayanlarda karşılaştırılması amacıyla yapılmıştır. Çalışmamız, Ağrı il merkezinde yaşayan 35 gebe ve 54 gebe olmayan bireyden oluşmaktadır. Çalışmamıza katılan bireylerden kişisel bilgi formları yüz yüze görüşme ile doldurularak toplandı. Katılmayı kabul eden bireylerden 2 cc kan numunesi alındı. Kan örnekleri santrifüjlenerek serum ve kan hücreleri birbirinden ayrıldı. Elde edilen sonuçlar, GraphPad Prism 9 programı ile istatistiksel analizleri yapıldı. Yaptığımız bu araştırmada katılımcıların yaş ortalamaları gebe bireylerde 25, gebe olmayanlarda ise 22 olduğu belirlendi. Gebelerin 83ünün sigara içmediği ve 96sının ise kronik hastalığının olmadığı tespit edildi. Çalışmaya katılan gebe olmayan bireylerin 6,31inin ise sigara kullandığı belirlendi. Elde edilen verilere göre sigara içen bayanların üç enzim için de hem serum hem de sitoplazma sonuçları daha düşük çıkmıştır. Gebelik durumunda ise sitoplazma AChE seviyeleri hariç bütün değerler azalmıştır.

Article Details

Investigation of the Effects of Smoking on Blood Metabolic Enzyme Activities in Pregnant Individuals

Authors:

Esra Şentürk | Gülpınar Aslan | Ela Varol | Murat Şentürk | Metin Yıldız

Publisher:

Gumushane University

Main Topics:

Sağlık Kurumları Yönetimi

Journal:

Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi Vol.13 Issue 1, pp.274-280

Document Type:

Article

Publication Date:

3/2024

Document Language:

Turkish

Document ID (Org No.):

2001313423

pISSN:

2146-9954

Pregnant women

Carbonic anhydrase

Catalase

Acetylcholinesterase

Glutathione peroxidaseAsetilkolinesteraz

Gebeler

Karbonik Anhidraz

Katalaz

Issues

Article Details

Authors: Esra Şentürk | Gülpınar Aslan | Ela Varol | Murat Şentürk | Metin Yıldız

Publisher: Gumushane University

Main Topics: Sağlık Kurumları Yönetimi

Journal: Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi Vol.13 Issue 1, pp.274-280

Document Type: Article

Publication Date: 3/2024

Document Language: Turkish

Document ID (Org No.): 2001313423

pISSN: 2146-9954

Issues

Authors:

Esra Şentürk | Gülpınar Aslan | Ela Varol | Murat Şentürk | Metin Yıldız

Publisher:

Gumushane University

Main Topics:

Sağlık Kurumları Yönetimi

Journal:

Gümüşhane Üniversitesi Sağlık Bilimleri Dergisi Vol.13 Issue 1, pp.274-280

Document Type:

Article

Publication Date:

3/2024

Document Language:

Turkish

Document ID (Org No.):

2001313423

pISSN:

2146-9954