Pathological, Immunohistochemical, and Electron Microscopic Findings in the Respiratory Tract and Skin of Chickens Naturally Infected with Avipoxvirus

Enver BEYTUT; Mehmet HALIGÜR

Article Details

Pathological, Immunohistochemical, and Electron Microscopic Findings in the Respiratory Tract and Skin of Chickens Naturally Infected with Avipoxvirus

Authors:

Enver BEYTUT | Mehmet HALIGÜR

Publisher:

TUBITAK

Main Topics:

Animal husbandry

Journal:

Turkish Journal of Veterinary and Animal Sciences 2007 Vol.31 Issue 5, pp.311-317

Document Type:

Article

Publication Date:

4/2007

Document Language:

English

Document ID (Org No.):

2000768127

Frequency:

Bimonthly

eISSN:

1303-6181

pISSN:

1300-0128

Keywords:

Abstract:

 

The present study describes pathological, immunohistochemical, and electron microscopic findings in the respiratory tract and skin of chickens naturally infected with avian pox virus. Respiratory distress, depression, and cyanosis were found in the chickens upon clinical examination. At necropsy, erosion, crusts, and nodules were observed on the comb, wattle, and eyelids. Histopathological examination revealed that the epithelial cells in the stratum spinosum were hyperplastic, and that their cytoplasm contained large, eosinophilic inclusion bodies. Epithelial hyperplasia was also prominent in the mucosa of the trachea and bronchi, with characteristic cytoplasmic inclusion bodies and severe submucosal accumulation of mononuclear cells. Avipoxvirus infection was confirmed by an immune positive reaction with antibodies against avipoxvirus within the cytoplasm of the hyperplastic epithelial cells and within the inclusion bodies, and by the electron microscopy of typical dumbbell-shaped poxviral particles within the epithelial cell inclusions.

 

The present study describes pathological, immunohistochemical, and electron microscopic findings in the respiratory tract and skin of chickens naturally infected with avian pox virus. Respiratory distress, depression, and cyanosis were found in the chickens upon clinical examination. At necropsy, erosion, crusts, and nodules were observed on the comb, wattle, and eyelids. Histopathological examination revealed that the epithelial cells in the stratum spinosum were hyperplastic, and that their cytoplasm contained large, eosinophilic inclusion bodies. Epithelial hyperplasia was also prominent in the mucosa of the trachea and bronchi, with characteristic cytoplasmic inclusion bodies and severe submucosal accumulation of mononuclear cells. Avipoxvirus infection was confirmed by an immune positive reaction with antibodies against avipoxvirus within the cytoplasm of the hyperplastic epithelial cells and within the inclusion bodies, and by the electron microscopy of typical dumbbell-shaped poxviral particles within the epithelial cell inclusions.

Article Details

Pathological, Immunohistochemical, and Electron Microscopic Findings in the Respiratory Tract and Skin of Chickens Naturally Infected with Avipoxvirus

Authors:

Enver BEYTUT | Mehmet HALIGÜR

Publisher:

TUBITAK

Main Topics:

Animal husbandry

Journal:

Turkish Journal of Veterinary and Animal Sciences 2007 Vol.31 Issue 5, pp.311-317

Document Type:

Article

Publication Date:

4/2007

Document Language:

English

Document ID (Org No.):

2000768127

Frequency:

Bimonthly

eISSN:

1303-6181

pISSN:

1300-0128

Chicken pox

pathology

immunohistochemistry

electron microscopy

skin

respiratory tract

Issues

Article Details

Pathological, Immunohistochemical, and Electron Microscopic Findings in the Respiratory Tract and Skin of Chickens Naturally Infected with Avipoxvirus

Authors: Enver BEYTUT | Mehmet HALIGÜR

Publisher: TUBITAK

Main Topics: Animal husbandry

Journal: Turkish Journal of Veterinary and Animal Sciences 2007 Vol.31 Issue 5, pp.311-317

Document Type: Article

Publication Date: 4/2007

Document Language: English

Document ID (Org No.): 2000768127

Frequency: Bimonthly

eISSN: 1303-6181

pISSN: 1300-0128

Chicken pox

pathology

immunohistochemistry

electron microscopy

skin

respiratory tract

Issues

Authors:

Enver BEYTUT | Mehmet HALIGÜR

Publisher:

TUBITAK

Main Topics:

Animal husbandry

Journal:

Turkish Journal of Veterinary and Animal Sciences 2007 Vol.31 Issue 5, pp.311-317

Document Type:

Article

Publication Date:

4/2007

Document Language:

English

Document ID (Org No.):

2000768127

Frequency:

Bimonthly

eISSN:

1303-6181

pISSN:

1300-0128