Nörodejeneratif Hastalık Araştırmalarında Drosophila melanogaster Modeli

Cem HAZIR; Gamze BORA; Hayat ERDEM YURTER

Article Details

Nörodejeneratif Hastalık Araştırmalarında Drosophila melanogaster Modeli

Authors:

Cem HAZIR | Gamze BORA | Hayat ERDEM YURTER

Publisher:

Bursa Uludağ University

Main Topics:

Human physiology | Surgery & related medical specialties

Journal:

Journal of Uludağ University Medical Faculty 2020 Vol.46 Issue 2, pp.237-245

Document Type:

Article

Publication Date:

7/2020

Document Language:

Turkish

Document ID (Org No.):

2000631904

Frequency:

Tri-annual

eISSN:

2645-9027

pISSN:

1300-414X

Abstract:

 


Modelling human diseases in Drosophila melanogaster have been accelerated advances in many areas including investigations on pathophysiology, identification of new genes and genetic modifiers, explanations of  clinic variability, development of new diagnosis and treatment approaches and drug investigations. In this review, advantages of D. melanogaster as a model organism and its use in neurodegenerative diseases are discussed.

Modelling human diseases in Drosophila melanogaster have been accelerated advances in many areas including investigations on pathophysiology, identification of new genes and genetic modifiers, explanations of clinic variability, development of new diagnosis and treatment approaches and drug investigations. In this review, advantages of D. melanogaster as a model organism and its use in neurodegenerative diseases are discussed.

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İnsan hastalıklarının Drosophila melanogaster’de modellenmesi sayesinde, patofizyolojilerin araştırılması, yeni genlerin ve genetik düzenleyicilerin tanımlanması, klinik çeşitlilik nedenlerinin açıklanabilmesi, yeni tanı ve tedavi yaklaşımlarının geliştirilmesi, ilaç araştırma çalışmalarının yapılabilmesi gibi birçok alandaki gelişmeler hız kazanmıştır.  Bu derlemede D. melaonogaster’in model organizma olarak avantajları ve nörodejeneratif hastalıklarla ilişkili araştırmalarda kullanılmasına ilişkin bilgiler verilmektedir.

Article Details

Nörodejeneratif Hastalık Araştırmalarında Drosophila melanogaster Modeli

Authors: Cem HAZIR | Gamze BORA | Hayat ERDEM YURTER

Publisher: Bursa Uludağ University

Main Topics: Human physiology | Surgery & related medical specialties

Journal: Journal of Uludağ University Medical Faculty 2020 Vol.46 Issue 2, pp.237-245

Document Type: Article

Publication Date: 7/2020

Document Language: Turkish

Document ID (Org No.): 2000631904

Frequency: Tri-annual

eISSN: 2645-9027

pISSN: 1300-414X

Issues

Authors:

Cem HAZIR | Gamze BORA | Hayat ERDEM YURTER

Publisher:

Bursa Uludağ University

Main Topics:

Human physiology | Surgery & related medical specialties

Journal:

Journal of Uludağ University Medical Faculty 2020 Vol.46 Issue 2, pp.237-245

Document Type:

Article

Publication Date:

7/2020

Document Language:

Turkish

Document ID (Org No.):

2000631904

Frequency:

Tri-annual

eISSN:

2645-9027

pISSN:

1300-414X