Phytochemical screening and biological activity of essential oils and flavonoïds of aromatic plant Salvia officinalis L in north-eastern Algeria

Benkherara Salah; Bordjiba Ou Ahiba; Boutlelis Djahra Ali

Article Details

Phytochemical screening and biological activity of essential oils and flavonoïds of aromatic plant Salvia officinalis L in north-eastern Algeria

Authors:

Benkherara Salah | Bordjiba Ou Ahiba | Boutlelis Djahra Ali

Publisher:

Phytochemistry & Organic Synthesis Laboratory

Journal:

PhytoChem & BioSub Journal Vol.9 Issue 2, pp.39-48

Document Type:

Article

Publication Date:

7/2015

Document Language:

English

Document ID (Org No.):

2001451425

pISSN:

2602-5132

Keywords:

Abstract:

 This study focuses on the evaluation of antibacterial biological activity of natural products of an
aromatic plant in the north-eastern Algeria: Salvia officinalis L. or officinal Sage. To do this and after a
phytochemical screening, essential oils and flavonoïds are extracted respectively by hydrodistillation and by
organic solvents according to the method of Charaux and Paris 1954. These compounds are thereafter identified
by GC/MS and TLC. Their antibacterial effect was determined, in vitro on Mueller-Hinton medium, towards
several bacterial strains responsible for certain infectious diseases. The results showed that the isolated essential
oil is characterized by a Chemotype with nineteen (19) terpene compounds with a prevalence of α-Thujone (about
37 %). Moreover, The TLC analysis of the obtained flavonoïque extract and the revelation by Aluminum
chloride (AlCl3) of the observed different tasks showed the presence of three compounds or groups of flavonoïque
compounds having frontal ratios between 0.128 and 0.928. The tests of antibacterial activity showed that growth
inhibition varies according to the bacterial species and the concentration of the extracted natural product. In
general, the essential oils have a very important inhibitory power against studied multiresistant germs.
Pseudomonas aeruginosa ATCC 27853 strain proved to be very sensitive face to different concentrations of the
obtained essential oils and flavonoïds with a maximum of inhibition of 37.08 and 45.92 mm of diameter
respectively, followed by the Escherichia coli 1429 strain, Escherichia Coli 1554, Proteus mirabilis and Klebsiella
pneumonia whose recorded inhibition zones usually exceed 30 mm in diameter. These results are promising and
provide a scientific validation as for the massive use of the plant Salvia officinalis L.

Article Details

Phytochemical screening and biological activity of essential oils and flavonoïds of aromatic plant Salvia officinalis L in north-eastern Algeria

Authors:

Benkherara Salah | Bordjiba Ou Ahiba | Boutlelis Djahra Ali

Publisher:

Phytochemistry & Organic Synthesis Laboratory

Journal:

PhytoChem & BioSub Journal Vol.9 Issue 2, pp.39-48

Document Type:

Article

Publication Date:

7/2015

Document Language:

English

Document ID (Org No.):

2001451425

pISSN:

2602-5132

Biological activity

essential oils

flavonoïds

Salvia officinalis

bacterial strains

Issues

Article Details

Phytochemical screening and biological activity of essential oils and flavonoïds of aromatic plant Salvia officinalis L in north-eastern Algeria

Authors: Benkherara Salah | Bordjiba Ou Ahiba | Boutlelis Djahra Ali

Publisher: Phytochemistry & Organic Synthesis Laboratory

Journal: PhytoChem & BioSub Journal Vol.9 Issue 2, pp.39-48

Document Type: Article

Publication Date: 7/2015

Document Language: English

Document ID (Org No.): 2001451425

pISSN: 2602-5132

Biological activity

essential oils

flavonoïds

Salvia officinalis

bacterial strains

Issues

Authors:

Benkherara Salah | Bordjiba Ou Ahiba | Boutlelis Djahra Ali

Publisher:

Phytochemistry & Organic Synthesis Laboratory

Journal:

PhytoChem & BioSub Journal Vol.9 Issue 2, pp.39-48

Document Type:

Article

Publication Date:

7/2015

Document Language:

English

Document ID (Org No.):

2001451425

pISSN:

2602-5132