Management of acute postoperative hypertension for reducing cardiovascular complications in cancer patients: when and how aggressively?

Ning LOU; Daofeng WANG; Zhi WANG; Wenfeng YE; Xiao LIU

Article Details

Management of acute postoperative hypertension for reducing cardiovascular complications in cancer patients: when and how aggressively?

Authors:

Ning LOU | Daofeng WANG | Zhi WANG | Wenfeng YE | Xiao LIU

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 6, pp.1634-1640

Document Type:

Article

Publication Date:

11/2016

Document Language:

Turkish

Document ID (Org No.):

2000751652

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Abstract:

 

Background/aim: We sought to determine what factors cardiovascular complications (CVCs) correlate with in cancer patients with acute postoperative hypertension (APH) and to define when and how aggressively to treat this disorder in the present study.  Materials and methods: A retrospective observational study of cancer patients with postoperative hypertension at a single intensive care unit between July 2007 and June 2013 was conducted. The outcome of interest was the incidence of a CVC.   Results: There were 1162 patients enrolled, of which 92 (7.9%) experienced one or more CVCs. Preexisting hypertension (OR 38.3, 95% CI 3.2-457.4, P = 0.004) and choice of vasodilator (OR 6.5, 95% CI 2.3-18.6, P = 0.000) were predictors of a CVC. Cardiovascular complications were less likely to occur if pain was relieved efficiently during the postoperative period (OR 15.9, 95% CI 1.9-130.1, P = 0.01). Furthermore, there were increased CVCs among patients with postoperative hypertensive crises compared to those with stage 1 or stage 2 hypertension with the treatment threshold for systolic blood pressure (OR 5.7, 95% CI 2.0-16.5, P = 0.001) or diastolic blood pressure (OR 6.0, 95% CI 1.8-20.3, P = 0.004).   Conclusion: To reduce CVCs, APH may be defined and managed as a hypertensive crisis in cancer patients.

Article Details

Management of acute postoperative hypertension for reducing cardiovascular complications in cancer patients: when and how aggressively?

Authors: Ning LOU | Daofeng WANG | Zhi WANG | Wenfeng YE | Xiao LIU

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2016 Vol.46 Issue 6, pp.1634-1640

Document Type: Article

Publication Date: 11/2016

Document Language: Turkish

Document ID (Org No.): 2000751652

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Issues

Authors:

Ning LOU | Daofeng WANG | Zhi WANG | Wenfeng YE | Xiao LIU

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 6, pp.1634-1640

Document Type:

Article

Publication Date:

11/2016

Document Language:

Turkish

Document ID (Org No.):

2000751652

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144