The Effectiveness of Different Treatment Modalities for Brain Arteriovenous Malformations in Providing a Seizure-Free and Neurological Deficit Free Outcome in Adult Patients : A Systematic Review

Nadir , Bakhtawar; Toriola , Tayo; Jamil , Maria; Gudapati , Deepika; Khan , Safeera

Article Details

The Effectiveness of Different Treatment Modalities for Brain Arteriovenous Malformations in Providing a Seizure-Free and Neurological Deficit Free Outcome in Adult Patients : A Systematic Review

Authors:

Nadir , Bakhtawar | Toriola , Tayo | Jamil , Maria | Gudapati , Deepika | Khan , Safeera

Publisher:

JOMENAS Press

Main Topics:

Medicine

Journal:

The Journal of Middle East and North Africa Sciences 2021 Vol.7 Issue 11, pp.19-34

Document Type:

Article

Publication Date:

11/2021

Document Language:

English

Document ID (Org No.):

241755

Frequency:

Monthly

eISSN:

24128937

pISSN:

24129763

Descriptors:

Keywords:

Abstract:

 An arteriovenous brain malformation is a disorder where there is a tangle of abnormal blood vessels that connect arteries and veins. Proper functioning of blood vessels is vital to the brain's oxygenation but with a brain arteriovenous malformation Â that disrupts oxygenating the brain. Arteriovenous malformations can occur anywhere, but they most commonly occur in the brain and spine. Once diagnosed, surgical treatment options are available to control and stop the disease, such as surgical resection, endovascular embolization, and stereotactic radiosurgery. The objective of this article is to determine the effectiveness of different treatment modalities for brain arteriovenous malformations in providing a seizurefree and neurological deficit free outcome in adult patients. An extensive literature search was conducted using PubMed and PubMed central as our main databases. The articles exploring the association and success rate between different treatment modalities and seizure and neurological-free outcomes were included. A total of 2066 studies were obtained by searching the databases, and after thorough screening, 29 studies were included for the review. This review highlights that microsurgery provides the best seizure control; however, if complete obliteration is achieved with stereotactic radiosurgery, then that offers the best control, and that is something that needs further investigation as there aren't as many studies on it. Moreover, we concluded that further investigations should be done on the combination therapy comprising embolization and stereotactic radiosurgery. It has great potential to provide a large percentage of the patients with this condition to achieve a seizure-free status.

Article Details

The Effectiveness of Different Treatment Modalities for Brain Arteriovenous Malformations in Providing a Seizure-Free and Neurological Deficit Free Outcome in Adult Patients : A Systematic Review

Authors:

Nadir , Bakhtawar | Toriola , Tayo | Jamil , Maria | Gudapati , Deepika | Khan , Safeera

Publisher:

JOMENAS Press

Main Topics:

Medicine

Journal:

The Journal of Middle East and North Africa Sciences 2021 Vol.7 Issue 11, pp.19-34

Document Type:

Article

Publication Date:

11/2021

Document Language:

English

Document ID (Org No.):

241755

Frequency:

Monthly

eISSN:

24128937

pISSN:

24129763

Descriptors:

BRAIN DISEASES

ARTERIES

BLOOD VESSELS

THERAPY

MICROSURGERY

PATIENTS

Brain Avms

Microsurgery

Stereotactic Surgery

Endovascular Embolization

Seizures Free Outcome (Seizures)

Issues

Article Details

Authors: Nadir , Bakhtawar | Toriola , Tayo | Jamil , Maria | Gudapati , Deepika | Khan , Safeera

Publisher: JOMENAS Press

Main Topics: Medicine

Journal: The Journal of Middle East and North Africa Sciences 2021 Vol.7 Issue 11, pp.19-34

Document Type: Article

Publication Date: 11/2021

Document Language: English

Document ID (Org No.): 241755

Frequency: Monthly

eISSN: 24128937

pISSN: 24129763

Descriptors:

Issues

Authors:

Nadir , Bakhtawar | Toriola , Tayo | Jamil , Maria | Gudapati , Deepika | Khan , Safeera

Publisher:

JOMENAS Press

Main Topics:

Medicine

Journal:

The Journal of Middle East and North Africa Sciences 2021 Vol.7 Issue 11, pp.19-34

Document Type:

Article

Publication Date:

11/2021

Document Language:

English

Document ID (Org No.):

241755

Frequency:

Monthly

eISSN:

24128937

pISSN:

24129763