The Efficacy of Iron and Piracetam in Breath Holding Spells and Levetiracetam in Anoxic Epileptic Seizures

Nezir Özgün; Osman Akdeniz; Muhittin Çelik; Hakan Sarbay; İzzettin Toktaş

Article Details

The Efficacy of Iron and Piracetam in Breath Holding Spells and Levetiracetam in Anoxic Epileptic Seizures

Authors:

Nezir Özgün | Osman Akdeniz | Muhittin Çelik | Hakan Sarbay | İzzettin Toktaş

Publisher:

Mardin Artuklu University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Artuklu International Journal of Health Sciences Vol.3 Issue 1, pp.18-23

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001287649

pISSN:

2792-0321

Keywords:

Abstract:

 Introduction: In this study, the patients diagnosed with breath holding spell BHS or anoxic epileptic seizures and initiated at least one out of iron or piracetam or levetiracetam therapies were evaluated. Material and Methods: We retrospectively evaluated 194 BHS patients. Iron therapy was initiated in case of iron deficiency anemia or case of ferritin values under 12 ngdl even if there was no anemia. The patients having no iron deficiency anemia, low ferritin and anoxic epileptic seizures were administered piracetam and the patients diagnosed with anoxic epileptic seizures were administered levetiracetam. Results: One hundred and eight patients 55.7 were male. The mean age was 21.3912.78 months. Iron therapy was initiated in 87 patients, piracetam to 96, and levetiracetam in 11 patients. Seizure numbers were manifestly decreased in all groups by the end of the first month after treatment concerning pretreatment levels p0.05. Conclusions: We determined that the spells were reduced or completely stopped in all groups. Levetiracetam seems to be considerably effective in patients developing anoxic epileptic seizures after BHS.

 Introduction: In this study, the patients diagnosed with breath holding spell BHS or anoxic epileptic seizures and initiated at least one out of iron or piracetam or levetiracetam therapies were evaluated. Material and Methods: We retrospectively evaluated 194 BHS patients. Iron therapy was initiated in case of iron deficiency anemia or case of ferritin values under 12 ngdl even if there was no anemia. The patients having no iron deficiency anemia, low ferritin and anoxic epileptic seizures were administered piracetam and the patients diagnosed with anoxic epileptic seizures were administered levetiracetam. Results: One hundred and eight patients 55.7 were male. The mean age was 21.3912.78 months. Iron therapy was initiated in 87 patients, piracetam to 96, and levetiracetam in 11 patients. Seizure numbers were manifestly decreased in all groups by the end of the first month after treatment concerning pretreatment levels p0.05. Conclusions: We determined that the spells were reduced or completely stopped in all groups. Levetiracetam seems to be considerably effective in patients developing anoxic epileptic seizures after BHS.

 Introduction: In this study, the patients diagnosed with breath holding spell BHS or anoxic epileptic seizures and initiated at least one out of iron or piracetam or levetiracetam therapies were evaluated. Material and Methods: We retrospectively evaluated 194 BHS patients. Iron therapy was initiated in case of iron deficiency anemia or case of ferritin values under 12 ngdl even if there was no anemia. The patients having no iron deficiency anemia, low ferritin and anoxic epileptic seizures were administered piracetam and the patients diagnosed with anoxic epileptic seizures were administered levetiracetam. Results: One hundred and eight patients 55.7 were male. The mean age was 21.3912.78 months. Iron therapy was initiated in 87 patients, piracetam to 96, and levetiracetam in 11 patients. Seizure numbers were manifestly decreased in all groups by the end of the first month after treatment concerning pretreatment levels p0.05. Conclusions: We determined that the spells were reduced or completely stopped in all groups. Levetiracetam seems to be considerably effective in patients developing anoxic epileptic seizures after BHS.

 Giriş: Bu çalışmada, katılma nöbeti veya anoksik epileptik nöbet tanısı alan ve demir, pirasetam veya levetirasetam tedavilerinden en az biri başlanan hastalarda, ilaçların nöbetleri azaltma etkinliği değerlendirilmiştir. Materyal and Metot: Çalışma kriterlerini karşılayan 194 hastanın dosyaları geriye dönuk olarak incelenmiştir. Demir eksikliği anemisi olan veya anemi olmasa bile ferritin değeri 12 ngdl altında olan hastalara demir tedavisi başlanmıştı. Anemi, duşuk ferritin ve anoksik epileptik nöbeti olmayan hastalara pirasetam, anoksik epileptik nöbeti olanlara levetirasetam başlanmıştı. Bulgular: Hastaların 108i  55.7 erkekti. Ortalama yaş 21.3912.78 aydı. 87 hastaya demir tedavisi, 96 hastaya pirasetam ve 11 hastaya levetirasetam başlanmıştı. Tedavi başlandıktan bir ay sonraki değerlendirmede tum gruplarda nöbet sayısı belirgin azalmıştı p0.05. Sonuç: Tum gruplarda nöbet sayısının azaldığını veya tam durduğunu saptadık. Levetirasetam katılma nöbeti sonrası gelişen anoksik epileptik nöbetlerde oldukça etkili gibi görunmektedir.

Article Details

The Efficacy of Iron and Piracetam in Breath Holding Spells and Levetiracetam in Anoxic Epileptic Seizures

Authors:

Nezir Özgün | Osman Akdeniz | Muhittin Çelik | Hakan Sarbay | İzzettin Toktaş

Publisher:

Mardin Artuklu University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Artuklu International Journal of Health Sciences Vol.3 Issue 1, pp.18-23

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001287649

pISSN:

2792-0321

Breath holding spell

Anoxic epileptic seizure

TreatmentKatılma nöbeti

Anoksik epileptik nöbet

Tedavi

Issues

Article Details

The Efficacy of Iron and Piracetam in Breath Holding Spells and Levetiracetam in Anoxic Epileptic Seizures

Authors: Nezir Özgün | Osman Akdeniz | Muhittin Çelik | Hakan Sarbay | İzzettin Toktaş

Publisher: Mardin Artuklu University

Main Topics: Klinik Tıp Bilimleri

Journal: Artuklu International Journal of Health Sciences Vol.3 Issue 1, pp.18-23

Document Type: Article

Publication Date: 12/2023

Document Language: English

Document ID (Org No.): 2001287649

pISSN: 2792-0321

Breath holding spell

Anoxic epileptic seizure

TreatmentKatılma nöbeti

Anoksik epileptik nöbet

Tedavi

Issues

Authors:

Nezir Özgün | Osman Akdeniz | Muhittin Çelik | Hakan Sarbay | İzzettin Toktaş

Publisher:

Mardin Artuklu University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Artuklu International Journal of Health Sciences Vol.3 Issue 1, pp.18-23

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001287649

pISSN:

2792-0321