NADPH-Diaphorase-Reactive Neurons in Rat Basal Ganglia

Gülgün KAYALIOĞLU

Article Details

NADPH-Diaphorase-Reactive Neurons in Rat Basal Ganglia

Authors:

Gülgün KAYALIOĞLU

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 4, pp.379-384

Document Type:

Article

Publication Date:

3/1999

Document Language:

Turkish

Document ID (Org No.):

2000757903

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Keywords:

Abstract:

 

NADPH-d reaction was performed on nine male Sprague-Dawley rats and morphometry of NADPH-d(+) cells was investigated in caudate-putamen, globus pallidus and ventral pallidum. In caudate-putamen we observed intensely   stained NADPH-d (+) cells. Maximum diameter and minimum diameters of the NADPH-d (+) cells in caudate-putamen was measured as 19.19±0.04 mm and 10.42±0.12 mm, consequently. In globus pallidus, moderately stained NADPH-d (+) cells were observed. We measured the maximum and minimum diameters of the NADPH-d (+) cells as 19.93±0.24 mm and 10.42±0.12 mm, consequently. In ventral pallidum, medium-sized, moderately stained cells were present. Maximum and minimum diameters of the NADPH-d (+) cells in ventral pallidum was 19.19±0.04 mm and   12.40±0.2 mm, consequently. NADPH-d (+) cells in caudate-putamen, globus pallidus and ventral pallidum were mostly multipolar in shape. Basal ganglia have recently been suggested to have a role in nociceptive processing. Based on the role of nitric oxide in nociception and NADPH-d which is a form of nitric oxide synthase, the positive reaction in these nuclei is proposed to have a role in nociception in basal ganglia.

 

NADPH-d reaction was performed on nine male Sprague-Dawley rats and morphometry of NADPH-d(+) cells was investigated in caudate-putamen, globus pallidus and ventral pallidum. In caudate-putamen we observed intensely   stained NADPH-d (+) cells. Maximum diameter and minimum diameters of the NADPH-d (+) cells in caudate-putamen was measured as 19.19±0.04 mm and 10.42±0.12 mm, consequently. In globus pallidus, moderately stained NADPH-d (+) cells were observed. We measured the maximum and minimum diameters of the NADPH-d (+) cells as 19.93±0.24 mm and 10.42±0.12 mm, consequently. In ventral pallidum, medium-sized, moderately stained cells were present. Maximum and minimum diameters of the NADPH-d (+) cells in ventral pallidum was 19.19±0.04 mm and   12.40±0.2 mm, consequently. NADPH-d (+) cells in caudate-putamen, globus pallidus and ventral pallidum were mostly multipolar in shape. Basal ganglia have recently been suggested to have a role in nociceptive processing. Based on the role of nitric oxide in nociception and NADPH-d which is a form of nitric oxide synthase, the positive reaction in these nuclei is proposed to have a role in nociception in basal ganglia.

Article Details

NADPH-Diaphorase-Reactive Neurons in Rat Basal Ganglia

Authors:

Gülgün KAYALIOĞLU

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 4, pp.379-384

Document Type:

Article

Publication Date:

3/1999

Document Language:

Turkish

Document ID (Org No.):

2000757903

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

caudate-putamen

globus pallidus

pallidum

NADPH-diaphorase.

Issues

Article Details

NADPH-Diaphorase-Reactive Neurons in Rat Basal Ganglia

Authors: Gülgün KAYALIOĞLU

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 1999 Vol.29 Issue 4, pp.379-384

Document Type: Article

Publication Date: 3/1999

Document Language: Turkish

Document ID (Org No.): 2000757903

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

caudate-putamen

globus pallidus

pallidum

NADPH-diaphorase.

Issues

Authors:

Gülgün KAYALIOĞLU

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 1999 Vol.29 Issue 4, pp.379-384

Document Type:

Article

Publication Date:

3/1999

Document Language:

Turkish

Document ID (Org No.):

2000757903

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144